HCCS Antibodies

AND HCCS ELISA kits, HCCS Proteins

Many biological assays use antibodies to detect HCCS, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HCCS in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HCCS antibodies...

We validate the specificity of these antibodies to HCCS by testing them on tissues known to express HCCS positively and negatively. Browse below to find the HCCS antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for HCCS? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the HCCS Western Blot Guide

HCCS Infographic by Boster Bio

All HCCS Products

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Product

Figures

Specificity

Applications

Price

Anti-HCCS Antibody Picoband®

Western blot analysis of HCCS using anti-HCCS antibody (A00924-2)

IHC analysis of HCCS using anti-HCCS antibody (A00924-2)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A00924-2
100 μg/vial

Anti-VPS53 Antibody

Western blot analysis of VPS53 in 293 cell lysate with VPS53 antibody at (A) 0

Immunocytochemistry of VPS53 in 293 cells with VPS53 antibody at 5 μg/mL

Immunofluorescence of VPS53 in 293 cells with VPS53 antibody at 2

Human, Mouse, Rat

ELISA, IF, ICC, WB

$481
Cat # A06836
0.1 mg

Anti-ZNF434 Antibody (Center)

Fluorescent image of MCF-7 cells stained with ZNF434 Antibody (Center)

Human

IF, WB

$299
Cat # A15854
80 µl

HCCS (NM_001122608) Human Over-expression Lysate

Human

$628
Cat # LS003052
20 µg, 100 µg

HCCS (NM_001122608) Human Recombinant Protein

Coomassie blue staining of purified HCCS protein

$1249
Cat # PROTP53701
20 µg

HCCS Overview

Facts about Cytochrome c-type heme lyase.

HCCS 3D structure. Source: alphafold

Cytochrome c-type heme lyase (HCCS)

Links covalently that the heme group to the apoprotein of cytochrome c.

Gene Information

Human
Gene Name:	HCCS
Uniprot:	P53701
Entrez:	3052

Family

Belongs to:

cytochrome c-type heme lyase family

Alternative Names

CCHLDKFZp779I1858; cytochrome c heme-lyase; cytochrome c-type heme lyase; EC 4.4.1.17; holocytochrome c synthase (cytochrome c heme-lyase); holocytochrome c synthase; Holocytochrome c-type synthase; MCOPS7

Molecular Weight

Mass (kDA):
30.602 kDA

Genomic Context


Human

Location:	Xp22.2
Sequence:	X; NC_000023.11 (11111332..11123086)

Subcellular Localizations

Mitochondrion inner membrane. Membrane; Lipid-anchor.

Diseases

Microphthalmos
Microphthalmia, Syndromic 7
Skin Abnormalities
Carcinoma
Neoplasms
Congenital Absence
Liver Carcinoma
Liver Neoplasms
Embryonic Mosaic
Mitochondrial Diseases
Malignant Neoplasms
Monosomy
Anophthalmos

Congenital Heart Defects
Hernia
Nerve Damage
Cardiomyopathies
Diaphragmatic Hernia
Limb Deformities, Congenital
Neoplasm Metastasis

Pathways

Transport
Neuron Death
Electron Transport
Pigmentation
Oxidative Phosphorylation
Localization
Methylation
Cell Death
Cell Growth
Cell Communication

Angiogenesis
Pathogenesis
Heart Development
Eye Development
Tissue Homeostasis

PTMs

Phosphorylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HCCS

References

PMID: 8661044 by Schaefer L., et al. Cloning and characterization of a putative human holocytochrome c- type synthetase gene (HCCS) isolated from the critical region for microphthalmia with linear skin defects (MLS).

PMID: 9674913 by van den Veyver I.B., et al. Genomic structure of a human holocytochrome c-type synthetase gene in Xp22.3 and mutation analysis in patients with Rett syndrome.