HERC4 Antibodies

AND HERC4 ELISA kits, HERC4 Proteins

Many biological assays use antibodies to detect HERC4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HERC4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HERC4 antibodies...

We validate the specificity of these antibodies to HERC4 by testing them on tissues known to express HERC4 positively and negatively. Browse below to find the HERC4 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HERC4 Infographic by Boster Bio

All HERC4 Products

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Anti-HERC4 Antibody Picoband®

Western blot analysis of HERC4 using anti-HERC4 antibody (A10089-1)

IHC analysis of HERC4 using anti-HERC4 antibody (A10089-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A10089-1
100 μg/vial

HERC4 Overview

Facts about Probable E3 ubiquitin-protein ligase HERC4.

HERC4 3D structure. Source: alphafold

Probable E3 ubiquitin-protein ligase HERC4 (HERC4)

Probable E3 ubiquitin-protein ligase involved in protein trafficking or in the distribution of cellular structures. Required for spermatozoon maturation and fertility, and for the elimination of the cytoplasmic droplet of the spermatozoon.

E3 ubiquitin-protein ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfer it to targeted substrates. .

Gene Information

Human
Gene Name:	HERC4
Uniprot:	Q5GLZ8
Entrez:	26091

Family

Belongs to:

No superfamily

Alternative Names

DKFZP564G092; EC 6.3.2; EC 6.3.2.-; HECT domain and RCC1-like domain-containing protein 4; hect domain and RLD 4; KIAA1593probable E3 ubiquitin-protein ligase HERC4

Molecular Weight

Mass (kDA):
118.563 kDA

Genomic Context


Human

Location:	10q21.3
Sequence:	10; NC_000010.11 (67921905..68075324, complement)

Tissue Specificity

Expressed in brain and testis and detected in heart and placenta.

Subcellular Localizations

Cytoplasm, cytosol. shows a punctate cytoplasmic distribution.

Diseases

Spastic Ataxia, Charlevoix-saguenay Type
Nervousness
Ataxia
Fish Diseases
Trauma, Nervous System
Punctate Inner Choroidopathy

Rna Virus Infections

Pathways

Swimming
Gene Silencing
Cell Cycle
Aging
Dna Repair
Localization

Spermatogenesis

PTMs

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HERC4

References

PMID: 15676274 by Hochrainer K., et al. The human HERC family of ubiquitin ligases: novel members, genomic organization, expression profiling, and evolutionary aspects.