HIVEP2 Antibodies

AND HIVEP2 ELISA kits, HIVEP2 Proteins

Many biological assays use antibodies to detect HIVEP2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HIVEP2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HIVEP2 antibodies...

We validate the specificity of these antibodies to HIVEP2 by testing them on tissues known to express HIVEP2 positively and negatively. Browse below to find the HIVEP2 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HIVEP2 Infographic by Boster Bio

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HIVEP2 Overview

Facts about Transcription factor HIVEP2.

HIVEP2 3D structure. Source: alphafold

Transcription factor HIVEP2 (HIVEP2)

This protein specifically binds to the DNA sequence 5'- GGGACTTTCC-3' that is found in the enhancer elements of numerous viral promoters like those of SV40, CMV, or HIV1. In addition, related sequences are found in the enhancer elements of a number of cellular promoters, including those of the class I MHC, interleukin-2 receptor, somatostatin receptor II, and interferon- beta genes.

It could act in T-cell activation. .

Gene Information

Human
Gene Name:	HIVEP2
Uniprot:	P31629
Entrez:	3097

Family

Belongs to:

No superfamily

Alternative Names

c-myc intron binding protein 1; c-myc intron-binding protein 1; human immunodeficiency virus type I enhancer binding protein 2; Human immunodeficiency virus type I enhancer-binding protein 2HIV-EP2MBP-2SHN2; MHC binding protein-2; MHC-binding protein 2; MIBP1; Schnurri-2; transcription factor HIVEP2; ZAS2; ZNF40B

Molecular Weight

Mass (kDA):
269.053 kDA

Genomic Context


Human

Location:	6q24.2
Sequence:	6; NC_000006.12 (142751469..142945756, complement)

Tissue Specificity

Expressed in brain and skeletal muscle.

Subcellular Localizations

Nucleus.

Diseases

Neoplasms
Inflammation
Nervousness
Neoplasm Metastasis
Lymphoma
Carcinoma
Immunologic Deficiency Syndromes
Malignant Neoplasms
Hiv Infections
Hyperplasia
Burkitt Lymphoma
Malignant Neoplasm Of Breast

Hepatitis B
Mammary Neoplasms
Central Nervous System Neoplasms
Liver Carcinoma
Hepatitis
Osteopenia
Leukemia

Pathways

Cell Growth
Cell Development
Methylation
Cell Death
Bone Remodeling
Bone Resorption
Osteoblast Differentiation
Brain Development
Aging
Immune Response
Hypersensitivity
Ossification
Nuclear Export

Inflammatory Response
Transcriptional Attenuation
Translation
Cell Differentiation
Histone Acetylation
Regulation Of Bone Remodeling
Regionalization

PTMs

Phosphorylation
Deacetylation

Acetylation
Methylation

Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HIVEP2

References

PMID: 2022670 by Nomura N., et al. HIV-EP2, a new member of the gene family encoding the human immunodeficiency virus type 1 enhancer-binding protein. Comparison with HIV-EP1/PRDII-BF1/MBP-1.

PMID: 1409593 by Van't Veer L.J., et al. Structure and expression of MBP-2: a 275 kDa zinc finger protein that binds to an enhancer of major histocompatibility complex class 1 genes.