HNF1A Antibodies

AND HNF1A ELISA kits, HNF1A Proteins

Many biological assays use antibodies to detect HNF1A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HNF1A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HNF1A antibodies...

We validate the specificity of these antibodies to HNF1A by testing them on tissues known to express HNF1A positively and negatively. Browse below to find the HNF1A antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for HNF1A? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the HNF1A Western Blot Guide

HNF1A Infographic by Boster Bio

All HNF1A Products

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Product

Figures

Specificity

Applications

Price

Anti-HNF1/HNF1A Antibody Picoband®

Western blot analysis of HNF1/HNF1A using anti-HNF1/HNF1A antibody (PB9214)

Human

$370
Cat # PB9214
100 μg/vial

HNF1 alpha (HNF1A) (NM_000545) Human Recombinant Protein

$1296
Cat # PROTP20823
20 µg

HNF1A Overview

Facts about Hepatocyte nuclear factor 1-alpha.

HNF1A 3D structure. Source: alphafold

Hepatocyte nuclear factor 1-alpha (HNF1A)

Transcriptional activator that modulates the tissue specific expression of multiple genes, especially in pancreatic islet cells and in liver. Required for the expression of several liver particular genes.

Binds to the inverted palindrome 5'- GTTAATNATTAAC-3'. .

Gene Information

Human
Gene Name:	HNF1A
Uniprot:	P20823
Entrez:	6927

Family

Belongs to:

HNF1 homeobox family

Alternative Names

HNF1 homeobox A; IDDM20; LFB1transcription factor 1, hepatic; LF-B1, hepatic nuclear factor (HNF1), albuminproximal factor; MODY3; TCF1hepatic; Transcription factor 1

Molecular Weight

Mass (kDA):
67.356 kDA

Genomic Context


Human

Location:	12q24.31
Sequence:	12; NC_000012.12 (120977683..121002512)

Tissue Specificity

Liver.

Subcellular Localizations

Nucleus.

Diseases

Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Maturity Onset Diabetes Mellitus In Young
Liver Carcinoma
Diabetes Mellitus, Insulin-dependent
Hyperglycemia
Liver Neoplasms
Neoplasms
Carcinoma
Insulin Resistance
Liver Neoplasms, Experimental
Obesity
Adenoma

Malignant Neoplasms
Hepatitis
Kidney Diseases
Hepatocellular Adenoma
Insulin Sensitivity
Hepatitis B
Inflammation

Interacting Proteins

DYRK1B
PROX1

Pathways

Secretion
Insulin Secretion
Pathogenesis
Transport
Regeneration
Glucose Homeostasis
Methylation
Liver Development
Localization
Cell Differentiation
Translation
Cell Proliferation
Cell Cycle

Hepatocyte Differentiation
Gluconeogenesis
Coagulation
Gene Silencing
Glycolysis
Hypersensitivity
Regulation Of Gene Expression

PTMs

Methylation
Phosphorylation
Oxidation
Acetylation
Hydroxylation

Glycosylation
Demethylation
Reduction
Cleavage
Ubiquitination

Deacetylation

Research Areas

Transcription Factors and Regulators

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HNF1A

References

PMID: 1707031 by Bach I., et al. Cloning of human hepatic nuclear factor 1 (HNF1) and chromosomal localization of its gene in man and mouse.

PMID: 7900999 by Bach I., et al. More potent transcriptional activators or a transdominant inhibitor of the HNF1 homeoprotein family are generated by alternative RNA processing.

1 Publications of Boster HNF1A Antibodies & ELISA Kits

PubMed ID: 28504115, Dai, X.Q., Cai, W.T., Wu, X., Chen, Y., & Han, F.M. (2017). Protocatechuic acid ...

*More publications can be found for each product on its corresponding product page