HSD3B2 Antibodies

AND HSD3B2 ELISA kits, HSD3B2 Proteins

Many biological assays use antibodies to detect HSD3B2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HSD3B2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HSD3B2 antibodies...

We validate the specificity of these antibodies to HSD3B2 by testing them on tissues known to express HSD3B2 positively and negatively. Browse below to find the HSD3B2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HSD3B2 Infographic by Boster Bio

All HSD3B2 Products

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Price

Anti-HSD3B2 Antibody

Human

$405
Cat # A02012
100ul

HSD3B2 (NM_000198) Human Recombinant Protein

$1062
Cat # PROTP26439
20 µg

HSD3B2 Overview

Facts about 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2.

HSD3B2 3D structure. Source: alphafold

3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 (HSD3B2)

3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.

Gene Information

Human
Gene Name:	HSD3B2
Uniprot:	P26439
Entrez:	3284

Family

Belongs to:

3-beta-HSD family

Alternative Names

3 beta-HSD type II; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II; 3-beta-HSD II; delta 5-delta 4-isomerase type II; HSD3B; HSDB; HSDB3B; hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2,3-beta-hydroxy-Delta(5)-steroid dehydrogenase; progesterone reductase; SDR11E2; short chain dehydrogenase/reductase family 11E, member 2,3-beta-hydroxy-5-ene steroid dehydrogenase

Molecular Weight

Mass (kDA):
42.052 kDA

Genomic Context


Human

Location:	1p12
Sequence:	1; NC_000001.11 (119414931..119423039)

Tissue Specificity

Expressed in adrenal gland, testis and ovary.

Subcellular Localizations

Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein.

Diseases

Malignant Neoplasms
Congenital Adrenal Hyperplasia
Hyperplasia
Adrenal Hyperplasia
Neoplasms
Malignant Neoplasm Of Prostate
Prostatic Neoplasms
Virilism
Polycystic Ovary Syndrome
Tumors Of Adrenal Cortex
Precocious Pubarche
Adenoma

Ambiguous Genitalia
Chronic Active Hepatitis
Precocious Puberty
Carcinoma
Malignant Neoplasm Of Adrenal Cortex
Adrenal Cortical Adenoma
Hypertensive Disease

Pathways

Secretion
Cell Proliferation
Cortisol Secretion
Ovulation
Transport
Cell Division
Dna Repair
Androgen Secretion
Cell Growth
Protein Phosphorylation
Progesterone Secretion
Immune Response
Spermatogenesis

Inflammatory Response
Reverse Transcription
Telomere Maintenance
Menarche
Lipid Transport
Hormone Secretion
Regulation Of Energy Homeostasis

PTMs

Cleavage

Phosphorylation

Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HSD3B2

References

PMID: 1741954 by Lachance Y., et al. Structure of the human type II 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase (3 beta-HSD) gene: adrenal and gonadal specificity.

PMID: 1944309 by Rheaume E., et al. Structure and expression of a new complementary DNA encoding the almost exclusive 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4- isomerase in human adrenals and gonads.