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- Table of Contents
Facts about 5-hydroxytryptamine receptor 7.
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Human | |
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Gene Name: | HTR7 |
Uniprot: | P34969 |
Entrez: | 3363 |
Belongs to: |
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G-protein coupled receptor 1 family |
5HT7; 5-HT7; 5-HT-7; 5-HT75-hydroxytryptamine receptor 7; 5-HT-X; 5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled); HTR7; serotonin 5-HT-7 receptor; Serotonin receptor 7
Mass (kDA):
53.555 kDA
Human | |
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Location: | 10q23.31 |
Sequence: | 10; NC_000010.11 (90738693..90858039, complement) |
Isoform A is the predominant isoform in spleen, caudate and hippocampus. Isoform B is expressed at lower levels. Isoform D is a minor isoform in terms of expression.
Cell membrane; Multi-pass membrane protein.
PMID: 9084407 by Heidmann D.E.A., et al. Four 5-hydroxytryptamine7 (5-HT7) receptor isoforms in human and rat produced by alternative splicing: species differences due to altered intron-exon organization.
PMID: 8226867 by Bard J.A., et al. Cloning of a novel human serotonin receptor (5-HT7) positively linked to adenylate cyclase.