Hyaluronidase-4 Antibodies

AND HYAL4 ELISA kits, Hyaluronidase-4 Proteins

Many biological assays use antibodies to detect Hyaluronidase-4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Hyaluronidase-4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Hyaluronidase-4 antibodies...

We validate the specificity of these antibodies to Hyaluronidase-4 by testing them on tissues known to express HYAL4 positively and negatively. Browse below to find the HYAL4 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HYAL4 Infographic by Boster Bio

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HYAL4 (NM_012269) Human Over-expression Lysate

Human

$628
Cat # LS023553
20 µg, 100 µg

HYAL4 Overview

Facts about Hyaluronidase-4.

HYAL4 3D structure. Source: alphafold

Hyaluronidase-4 (HYAL4)

Endo-hyaluronidase that degrades hyaluronan to smaller oligosaccharide fragments. Has also chondroitin sulfate hydrolase activity, The ideal substrate being the galactosaminidic linkage in the sequence of a trisulfated tetrasaccharide.

Gene Information

Human
Gene Name:	HYAL4
Uniprot:	Q2M3T9
Entrez:	23553

Family

Belongs to:

glycosyl hydrolase 56 family

Alternative Names

chondroitin sulfate hydrolase; CSHY; EC 3.2.1; EC 3.2.1.35; HYAL4; Hyal-4; Hyaluronidase 4; hyaluronidase-4; hyaluronoglucosaminidase 4; hyaluronoglucosaminidase-4

Molecular Weight

Mass (kDA):
54.249 kDA

Genomic Context


Human

Location:	7q31.32
Sequence:	7; NC_000007.14 (123763708..123877481)

Tissue Specificity

Detected in placenta and skeletal muscle.

Subcellular Localizations

Membrane; Multi-pass membrane protein.

Diseases

Mucopolysaccharidoses
Neoplasms

Pathways

Cartilage Development
Acrosome Reaction
Glycosylation
Localization

PTMs

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HYAL4

References

PMID: 10493834 by Csoka A.B., et al. Expression analysis of six paralogous human hyaluronidase genes clustered on chromosomes 3p21 and 7q31.

PMID: 19889881 by Kaneiwa T., et al. Identification of human hyaluronidase-4 as a novel chondroitin sulfate hydrolase that preferentially cleaves the galactosaminidic linkage in the trisulfated tetrasaccharide sequence.