HADHA Antibodies

AND HADHA ELISA kits, HADHA Proteins

Many biological assays use antibodies to detect HADHA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HADHA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HADHA antibodies...

We validate the specificity of these antibodies to HADHA by testing them on tissues known to express HADHA positively and negatively. Browse below to find the HADHA antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for HADHA? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the HADHA IHC Guide

HADHA Infographic by Boster Bio

All HADHA Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-HADHA Antibody Picoband®

Western blot analysis of HADHA using anti-HADHA antibody (A03666-2)

IHC analysis of HADHA using anti-HADHA antibody (A03666-2)

+16

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A03666-2
100 μg/vial

HADHA (NM_000182) Human Over-expression Lysate

Human

$628
Cat # LS003030
20 µg, 100 µg

HADHA Overview

Facts about Trifunctional enzyme subunit alpha, mitochondrial.

HADHA 3D structure. Source: alphafold

Trifunctional enzyme subunit alpha, mitochondrial (HADHA)

Bifunctional subunit. .

Gene Information

Human
Gene Name:	HADHA
Uniprot:	P40939
Entrez:	3030

Family

Belongs to:

No superfamily

Alternative Names

3-ketoacyl-Coenzyme A (CoA) thiolase, alpha subunit; 3-oxoacyl-CoA thiolase; 78 kDa gastrin-binding protein; ECHA; gastrin-binding protein; GBP; HADH; hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase(trifunctional protein), alpha subunit; hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme Athiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit; LCEH; LCHAD; long-chain 2-enoyl-CoA hydratase; long-chain-3-hydroxyacyl-CoA dehydrogenase; MGC1728; mitochondrial long-chain 2-enoyl-Coenzyme A (CoA) hydratase, alpha subunit; mitochondrial long-chain L

Molecular Weight

Mass (kDA):
83 kDA

Genomic Context


Human

Location:	2p23.3
Sequence:	2; NC_000002.12 (26190635..26244632, complement)

Subcellular Localizations

Mitochondrion. Mitochondrion inner membrane. Protein stability and association with mitochondrion inner membrane do not require HADHB.

Diseases

Mitochondrial Trifunctional Protein Deficiency
Protein Deficiency
Cardiomyopathies
Abetalipoproteinemia
Deficiency Of 3-hydroxyacyl-coa Dehydrogenase
Mitochondrial Diseases
Hypoglycemia
Fatty Liver
Rhabdomyolysis
Pregnancy Complications
Sudden Infant Death Syndrome
Malignant Neoplasms
Muscle Hypotonia

Hypertrophy
Liver Diseases
Liver Failure
Neoplasm Metastasis
Carcinoma
Myopathy
Acidosis

Interacting Proteins

GABARAP
GABARAPL1
GABARAPL2
MAP1LC3B

Pathways

Fatty Acid Oxidation
Fatty Acid Beta-oxidation
Localization
Senescence
Translation
Hypersensitivity
Pathogenesis

Muscle Atrophy

PTMs

Oxidation

Phosphorylation

Reduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HADHA

References

PMID: 8135828 by Kamijo T., et al. Structural analysis of cDNAs for subunits of human mitochondrial fatty acid beta-oxidation trifunctional protein.

PMID: 7918661 by Zhang Q.X., et al. Structures of the human cDNA and gene encoding the 78 kDa gastrin- binding protein and of a related pseudogene.