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- Table of Contents
Hes5 Antibodies
AND Hes5 ELISA kits, Hes5 Proteins
Many biological assays use antibodies to detect Hes5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Hes5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Hes5 antibodies...
Designing a Western blot for Hes5? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the HES5 Western Blot GuideDesigning an IHC experiment for Hes5? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the HES5 IHC GuideHes5 Infographic by Boster Bio
All Hes5 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, IF, IHC-P, WB
$481
Cat # A05384
0.1 mg
Cat # A05384
0.1 mg
Hes5 Overview
Facts about Transcription factor HES-5.
Transcription factor HES-5 (Hes5)
Transcriptional repressor of genes that require a bHLH protein for their transcription. Plays a significant role as neurogenesis negative regulator.
.
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Hes5 |
| Uniprot: | P70120 |
| Entrez: | 15208 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
BHLHB38; bHLHb38Class B basic helix-loop-helix protein 38; hairy and enhancer of split 5 (Drosophila); Hairy and enhancer of split 5; transcription factor HES-5
Molecular Weight
Mass (kDA):
18.425 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 4 E2|4 86.01 cM |
| Sequence: | 4; |
Diseases
- Nervousness
- Idiopathic Hypereosinophilic Syndrome
- Neoplasms
- Malignant Neoplasms
- Carcinoma
- Depressive Disorder
- Cell Transformation, Neoplastic
- Brain Neoplasms
- Inflammation
- Malignant Neoplasm Of Breast
- Ischemia
- Cancer Patients And Suicide And Depression
Pathways
- Neurogenesis
- Notch Signaling Pathway
- Cell Differentiation
- Cell Proliferation
- Cell Cycle
- Regeneration
- Lateral Inhibition
- Hair Cell Differentiation
- Gliogenesis
- Cell Development
- Segmentation
- Pathogenesis
- Brain Development
PTMs
- Phosphorylation
- Cleavage
- Methylation
- Deacetylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Hes5
bosterbio.com/bosterbio-gene-info-cards/Hes5
References
PMID: 7836401 by Takebayashi K., et al. Structure and promoter analysis of the gene encoding the mouse helix- loop-helix factor HES-5. Identification of the neural precursor cell- specific promoter element.
PMID: 23160044 by Tiberi L., et al. BCL6 controls neurogenesis through Sirt1-dependent epigenetic repression of selective Notch targets.