Hmgn5 Antibodies

AND Hmgn5 ELISA kits, Hmgn5 Proteins

Many biological assays use antibodies to detect Hmgn5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Hmgn5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Hmgn5 antibodies...

We validate the specificity of these antibodies to Hmgn5 by testing them on tissues known to express Hmgn5 positively and negatively. Browse below to find the Hmgn5 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Hmgn5 Overview

Facts about High mobility group nucleosome-binding domain-containing protein 5.

High mobility group nucleosome-binding domain-containing protein 5 (Hmgn5)

Preferentially binds to euchromatin and modulates cellular transcription by counteracting linker histone-mediated chromatin compaction. .

Gene Information

Mouse
Gene Name:	Hmgn5
Uniprot:	Q9JL35
Entrez:	50887

Family

Belongs to:

HMGN family

Alternative Names

high mobility group nucleosome-binding domain-containing protein 5; high-mobility group nucleosome binding domain 5; NBP-45; NSBP1nucleosomal binding protein 1; Nucleosome-binding protein 1

Molecular Weight

Mass (kDA):
45.344 kDA

Genomic Context


Mouse

Location:	X\|X D
Sequence:	X;

Tissue Specificity

Expressed in liver, spleen, lung, heart, kidney, muscle and brain (at protein level). Widely expressed with highest levels in submaxillary gland, thymus, kidney and liver and lowest levels in brain, lung, pancreas and eye.

Diseases

Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Prostate
Prostatic Neoplasms
Carcinoma
Cell Transformation, Neoplastic
Malignant Neoplasm Of Breast
Neoplasm Invasiveness
Malignant Neoplasm Of Urinary Bladder
Cell Invasion
Carcinoma, Transitional Cell
Neoplasm Metastasis

Metastatic Malignant Neoplasm To The Lymph Node
Endometrial Adenocarcinoma
Head And Neck Carcinoma
Glioma
Kidney Neoplasm
Oral Cavity Carcinoma
Malignant Neoplasm Of Lung

Pathways

Cell Cycle
Cell Proliferation
Cell Cycle Arrest
Rna Interference
S Phase
G1 Phase
Dna Repair
Localization

Double-strand Break Repair
Chromatin Remodeling

PTMs

Phosphorylation

Research Areas

Core ESC-Like Genes
Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Hmgn5

References

PMID: 10692437 by Shirakawa H., et al. NBP-45, a novel nucleosomal binding protein with a tissue-specific and developmentally regulated expression.

PMID: 19160411 by Shirakawa H., et al. The nucleosomal binding protein NSBP1 is highly expressed in the placenta and modulates the expression of differentiation markers in placental Rcho-1 cells.