HNMT Antibodies

AND HNMT ELISA kits, HNMT Proteins

Many biological assays use antibodies to detect HNMT, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HNMT in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HNMT antibodies...

We validate the specificity of these antibodies to HNMT by testing them on tissues known to express HNMT positively and negatively. Browse below to find the HNMT antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HNMT Infographic by Boster Bio

All HNMT Products

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Figures

Specificity

Applications

Price

Anti-Histamine N-methyltransferase HNMT Antibody

Western blot analysis of extracts of various cell lines, using HNMT antibody at 1:1000 dilution

Immunoprecipitation analysis of 200ug extracts of HT-29 cells using 1ug HNMT antibody

Human, Mouse

IP, WB

$405
Cat # A03807
100ul

Human Histamine N-Methyltransferase/HNMT Recombinant Protein

SDS-PAGE

$250
Cat # PROTP50135
Starting from 20ug

HNMT (NM_006895) Human Over-expression Lysate

Human

$628
Cat # LS003176
20 µg, 100 µg

Human HNMT ELISA Kit PicoKine®

1 Citations

Human

ELISA

$750
Cat # EK2216
96 wells/kit, with removable strips.

HNMT Overview

Facts about Histamine N-methyltransferase.

HNMT 3D structure. Source: alphafold

Histamine N-methyltransferase (HNMT)

Inactivates histamine by N-methylation.
Plays an important role in degrading histamine and in regulating the airway response to histamine.

Gene Information

Human
Gene Name:	HNMT
Uniprot:	P50135
Entrez:	3176

Family

Belongs to:

class I-like SAM-binding methyltransferase superfamily

Alternative Names

EC 2.1.1.8; Histamine NMethyltransferase; Histamine N-Methyltransferase; HMT; HNMT; HNMT-S1; HNMT-S2

Molecular Weight

Mass (kDA):
33.295 kDA

Genomic Context


Human

Location:	2q22.1
Sequence:	2; NC_000002.12 (137964068..138016364)

Subcellular Localizations

Cytoplasm.

Diseases

Asthma
Hypotension Adverse Event
Nervousness
Parkinson Disease
Inflammation
Ulcer
Hemorrhage
Allergy
Alzheimer's Disease
Urticaria
Disease Of Adrenal Medulla
Rhinorrhea

Shock, Hemorrhagic
Essential Tremor
Neoplasms
Pituitary Diseases
Dysequilibrium Syndrome
Allergic Asthma
Hypokinesia

Pathways

Pathogenesis
Methylation
Secretion
Hypersensitivity
Gastric Acid Secretion
Acid Secretion
Cognition
Cell Proliferation
Localization
Translation
Cell Activation
Smooth Muscle Contraction
Anaphylaxis

Regulation Of Gastric Acid Secretion
Immune Response
Muscle Contraction
Energy Homeostasis
Cortisol Secretion
Mast Cell Activation
Histamine Uptake

PTMs

Methylation
Phosphorylation

Reduction
Deamination

Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HNMT

References

PMID: 7943261 by Yamauchi K., et al. Structure and function of human histamine N-methyltransferase: critical enzyme in histamine metabolism in airway.

PMID: 8145732 by Girard B., et al. Human histamine N-methyltransferase pharmacogenetics: cloning and expression of kidney cDNA.