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- Table of Contents
HNRNPC Antibodies
AND HNRNPC ELISA kits, HNRNPC Proteins
Many biological assays use antibodies to detect HNRNPC, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HNRNPC in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HNRNPC antibodies...
Designing a Western blot for HNRNPC? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the HNRNPC Western Blot GuideDesigning an IHC experiment for HNRNPC? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the HNRNPC IHC GuideHNRNPC Infographic by Boster Bio
All HNRNPC Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M02726
100 μl
Cat # M02726
100 μl
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A02726-1
100 μl/vial
Cat # A02726-1
100 μl/vial
Human, Mouse, Rat
ELISA
$540
Cat # EKC2290
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2290
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1279
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1279
1 kit, containing one 96-well plate and all necessary reagents
HNRNPC Overview
Facts about Heterogeneous nuclear ribonucleoproteins C1/C2.
Heterogeneous nuclear ribonucleoproteins C1/C2 (HNRNPC)
Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles (PubMed:8264621). Interacts with poly-U tracts from the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules (PubMed:12509468, PubMed:16010978, PubMed:7567451, PubMed:8264621).
Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides (PubMed:8264621).
Gene Information
| Human | |
|---|---|
| Gene Name: | HNRNPC |
| Uniprot: | P07910 |
| Entrez: | 3183 |
Family
| Belongs to: |
|---|
| RRM HNRPC family |
Alternative Names
C1; C2; heterogeneous nuclear ribonucleoprotein C (C1/C2); heterogeneous nuclear ribonucleoproteins C1/C2; hnRNP C1/C2; HNRNP; hnRNPC; HNRPC; MGC104306; MGC105117; MGC117353; MGC131677; nuclear ribonucleoprotein particle C1 protein; nuclear ribonucleoprotein particle C2 protein; SNRPC
Molecular Weight
Mass (kDA):
33.67 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 14q11.2 |
| Sequence: | 14; NC_000014.9 (21209136..21269479, complement) |
Subcellular Localizations
Nucleus. Component of ribonucleosomes.
Diseases
- Neoplasms
- Malignant Neoplasms
- Neoplasm Metastasis
- Rheumatism
- Mammary Neoplasms
- Arthritis, Psoriatic
- Arthritis
- Inflammation
- Shwachman Syndrome
- Telomere Shortening
- Cell Transformation, Neoplastic
- Glioblastoma Multiforme
Interacting Proteins
- CDC5L
- DDX21
- EPS8
- HNRNPA1
- HNRNPCL2
- KPNA2
- KPNA3
- KPNA4
- LMO2
- RALY
Pathways
- Translation
- Transport
- Cell Proliferation
- Rna Processing
- Protein Phosphorylation
- Programmed Cell Death
- Interphase
- Dna Repair
- Rna Splicing
- Cell Death
- Pathogenesis
- Cell Adhesion
- Hyperphosphorylation
PTMs
- Phosphorylation
- Cleavage
Research Areas
- DNA Repair
- DNA replication, Transcription, Translation and Splicing
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HNRNPC
bosterbio.com/bosterbio-gene-info-cards/HNRNPC
References
PMID: 2557628 by Burd C.G., et al. Primary structures of the heterogeneous nuclear ribonucleoprotein A2, B1, and C2 proteins: a diversity of RNA binding proteins is generated by small peptide inserts.
PMID: 3110598 by Swanson M.S., et al. Primary structure of human nuclear ribonucleoprotein particle C proteins: conservation of sequence and domain structures in heterogeneous nuclear RNA, mRNA, and pre-rRNA-binding proteins.