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- Table of Contents
Facts about Intraflagellar transport protein 27 homolog.
Required for hedgehog signaling. Forms a subcomplex within the IFT complex B with IFT25.
| Human | |
|---|---|
| Gene Name: | IFT27 |
| Uniprot: | Q9BW83 |
| Entrez: | 11020 |

| Belongs to: |
|---|
| small GTPase superfamily |

intraflagellar transport 27 homolog (Chlamydomonas); intraflagellar transport protein 27 homolog; member of RAS oncogene family-like 4; Putative GTP-binding protein RAY-like; RABL4; Rab-like protein 4
Mass (kDA):
20.48 kDA

| Human | |
|---|---|
| Location: | 22q12.3 |
| Sequence: | 22; NC_000022.11 (36758208..36776119, complement) |
Cell projection, cilium. Cytoplasm. Cell projection, cilium, flagellum. Localizes to the sperm flagellum.






PMID: 12529303 by Collins J.E., et al. Reevaluating human gene annotation: a second-generation analysis of chromosome 22.
PMID: 24488770 by Aldahmesh M.A., et al. IFT27, encoding a small GTPase component of IFT particles, is mutated in a consanguineous family with Bardet-Biedl syndrome.