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- Table of Contents
IGBP1 Antibodies
AND IGBP1 ELISA kits, IGBP1 Proteins
Many biological assays use antibodies to detect IGBP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IGBP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IGBP1 antibodies...
Designing a Western blot for IGBP1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the IGBP1 Western Blot GuideIGBP1 Infographic by Boster Bio
All IGBP1 Products
Product
Figures
Specificity
Applications
Price
Human
Flow Cytometry, IF, WB
$523
Cat # M05930
100 µl
Cat # M05930
100 µl
IGBP1 Overview
Facts about Immunoglobulin-binding protein 1.
Immunoglobulin-binding protein 1 (IGBP1)
Associated to surface IgM-receptor; may be involved in signal transduction. Involved in regulation of the catalytic activity of the phosphatases PP2A, PP4 and PP6 by protecting their partly folded catalytic subunits from degradative polyubiquitination until they associate with regulatory subunits.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | IGBP1 |
| Uniprot: | P78318 |
| Entrez: | 3476 |
Family
| Belongs to: |
|---|
| IGBP1/TAP42 family |
Alternative Names
ALPHA-4; B cell signal transduction molecule alpha 4; bA351K23.1 (immunoglobulin binding protein 1 (CD79A) ); B-cell signal transduction molecule alpha 4; CD79a-binding protein 1; IBP1; immunoglobulin (CD79A) binding protein 1; immunoglobulin-binding protein 1; Protein alpha-4; protein phosphatase 2A, regulatory subunit alpha-4; Renal carcinoma antigen NY-REN-16
Molecular Weight
Mass (kDA):
39.222 kDA
Genomic Context
| Human | |
|---|---|
| Location: | Xq13.1 |
| Sequence: | X; NC_000023.11 (70133447..70166324) |
Tissue Specificity
Ubiquitously expressed with highest levels in heart, skeletal muscle and pancreas.
Subcellular Localizations
Cytoplasm.
Diseases
- Malignant Neoplasms
- Neoplasms
- Lymphoma
- Hyperplasia
- Carcinoma
- Multiple Myeloma
- Adenocarcinoma
- Cell Transformation, Neoplastic
- Lung Neoplasms
- Congenital Ocular Coloboma (disorder)
- Stenosis
- Neoplasms, Radiation-induced
- Atresia
Interacting Proteins
- HSPB1
- MID1
- PPP2CA
- PPP2CB
- PPP4C
- PPP6C
- TIPRL
Pathways
- Cell Proliferation
- Translation
- Cell Growth
- Localization
- Cell Cycle
- Regulation Of Phosphatase Activity
- Cell Activation
- Cell Migration
- Dna Hypomethylation
- Cell Development
PTMs
- Phosphorylation
- Dephosphorylation
Research Areas
- Protein Phosphatase
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IGBP1
bosterbio.com/bosterbio-gene-info-cards/IGBP1
References
PMID: 9441740 by Onda M., et al. Expression and chromosomal localization of the human alpha 4/IGBP1 gene, the structure of which is closely related to the yeast TAP42 protein of the rapamycin-sensitive signal transduction pathway.
PMID: 9647778 by Chen J., et al. Alpha 4 associates with protein phosphatases 2A, 4, and 6.