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- Table of Contents
IGFBP4 Antibodies
AND IGFBP4 ELISA kits, IGFBP4 Proteins
Many biological assays use antibodies to detect IGFBP4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IGFBP4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IGFBP4 antibodies...
Designing a Western blot for IGFBP4? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the IGFBP4 Western Blot GuideIGFBP4 Infographic by Boster Bio
All IGFBP4 Products
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IGFBP4 Overview
Facts about Insulin-like growth factor-binding protein 4.
Insulin-like growth factor-binding protein 4 (IGFBP4)
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
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Gene Information
| Human | |
|---|---|
| Gene Name: | IGFBP4 |
| Uniprot: | P22692 |
| Entrez: | 3487 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
BP-4; HT29-IGFBP; IBP4insulin-like growth factor-binding protein 4; IGF-binding protein 4; IGFBP4; IGFBP-4; IGFBP-4IBP-4; insulin-like growth factor binding protein 4
Molecular Weight
Mass (kDA):
27.934 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17q21.2 |
| Sequence: | 17; NC_000017.11 (40443450..40457725) |
Subcellular Localizations
Secreted.
Diseases
- Malignant Neoplasms
- Neoplasms
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Carcinoma
- Hypertrophy
- Atrophy
- Inflammation
- Cell Transformation, Neoplastic
- Tumor Angiogenesis
- Adenocarcinoma
- Malignant Paraganglionic Neoplasm
- Fracture
Interacting Proteins
- IGF1
Pathways
- Cell Proliferation
- Cell Growth
- Secretion
- Transport
- Cell Cycle
- Localization
- Cell Adhesion
- Ovulation
- Proteolysis
- Angiogenesis
- Luteinization
- Cell Division
- Oocyte Maturation
PTMs
- Cleavage
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IGFBP4
bosterbio.com/bosterbio-gene-info-cards/IGFBP4
References
PMID: 1704481 by Shimasaki S., et al. Molecular cloning of the cDNAs encoding a novel insulin-like growth factor-binding protein from rat and human.
PMID: 1707125 by Latour D., et al. Inhibitory insulin-like growth factor-binding protein: cloning, complete sequence, and physiological regulation.