IGHV3-7 Antibodies

AND IGHV3-7 ELISA kits, IGHV3-7 Proteins

Many biological assays use antibodies to detect IGHV3-7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IGHV3-7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IGHV3-7 antibodies...

We validate the specificity of these antibodies to IGHV3-7 by testing them on tissues known to express IGHV3-7 positively and negatively. Browse below to find the IGHV3-7 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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IGHV3-7 Infographic by Boster Bio

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IGHV3-7 Overview

Facts about Immunoglobulin heavy variable 3-7.

IGHV3-7 3D structure. Source: alphafold

Immunoglobulin heavy variable 3-7 (IGHV3-7)

V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition (PubMed:24600447). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.

In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268).

Gene Information

Human
Gene Name:	IGHV3-7
Uniprot:	P01780
Entrez:	28452

Family

Belongs to:

No superfamily

Alternative Names

Immunoglobulin heavy variable 3-7

Molecular Weight

Mass (kDA):
12.943 kDA

Genomic Context


Human

Location:	14q32.33
Sequence:	14; NC_000014.9 (106062149..106062604, complement)

Subcellular Localizations

Secreted. Cell membrane.

PTMs

Disulfide bond

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IGHV3-7

References

PMID: 4803843 by Watanabe S., et al. The primary structure of a monoclonal IgM-immunoglobulin (macroglobulin Gal.), II: the amino acid sequence of the H-chain (mu- type), subgroup H III. Architecture of the complete IgM-molecule.

PMID: 4522793 by Capra J.D., et al. Variable region sequences of five human immunoglobulin heavy chains of the VH3 subgroup: definitive identification of four heavy chain hypervariable regions.