IGHV4-31 Antibodies

AND IGHV4-31 ELISA kits, IGHV4-31 Proteins

Many biological assays use antibodies to detect IGHV4-31, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IGHV4-31 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IGHV4-31 antibodies...

We validate the specificity of these antibodies to IGHV4-31 by testing them on tissues known to express IGHV4-31 positively and negatively. Browse below to find the IGHV4-31 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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IGHV4-31 Infographic by Boster Bio

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IGHV4-31 Overview

Facts about Immunoglobulin heavy variable 4-31.

IGHV4-31 3D structure. Source: alphafold

Immunoglobulin heavy variable 4-31 (IGHV4-31)

V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition (PubMed:24600447). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.

In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268).

Gene Information

Human
Gene Name:	IGHV4-31
Uniprot:	P0DP07
Entrez:	28396

Family

Belongs to:

No superfamily

Alternative Names

Immunoglobulin heavy variable 4-31

Molecular Weight

Mass (kDA):
13.095 kDA

Genomic Context


Human

Location:	14q32.33
Sequence:	14;

Subcellular Localizations

Secreted. Cell membrane.

PTMs

Disulfide bond

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IGHV4-31

References

PMID: 23541343 by Watson C.T., et al. Complete haplotype sequence of the human immunoglobulin heavy-chain variable, diversity, and joining genes and characterization of allelic and copy-number variation.