IGKV1-33 Antibodies

AND IGKV1-33 ELISA kits, IGKV1-33 Proteins

Many biological assays use antibodies to detect IGKV1-33, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IGKV1-33 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IGKV1-33 antibodies...

We validate the specificity of these antibodies to IGKV1-33 by testing them on tissues known to express IGKV1-33 positively and negatively. Browse below to find the IGKV1-33 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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IGKV1-33 Infographic by Boster Bio

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IGKV1-33 Overview

Facts about Immunoglobulin kappa variable 1-33.

IGKV1-33 3D structure. Source: alphafold

Immunoglobulin kappa variable 1-33 (IGKV1-33)

V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.

In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414).

Gene Information

Human
Gene Name:	IGKV1-33
Uniprot:	P01594
Entrez:	28933

Family

Belongs to:

No superfamily

Alternative Names

Immunoglobulin kappa variable 1-33

Molecular Weight

Mass (kDA):
12.848 kDA

Genomic Context


Human

Location:	2p11.2
Sequence:	2; NC_000002.12 (89268001..89268475, complement)

Subcellular Localizations

Secreted. Cell membrane.

PTMs

Disulfide bond

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IGKV1-33

References

PMID: 5028201 by Schiechl H., et al. Rule of antibody structure. The primary structure of a monoclonal immunoglobulin L-chain of the kappa-type, subgroup I (Bence-Jones protein Au).

PMID: 818073 by Shinoda T.; Comparative structural studies on the light chains of human immunoglobulins. I. Protein Ka with the Inv(3) allotypic marker.