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- Table of Contents
Facts about Immunoglobulin kappa variable 1D-33.
In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414).
Human | |
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Gene Name: | IGKV1D-33 |
Uniprot: | P01593 |
Entrez: | 28896 |
Belongs to: |
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No superfamily |
Immunoglobulin kappa variable 1D-33
Mass (kDA):
12.848 kDA
Human | |
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Location: | 2p11.2 |
Sequence: | 2; NC_000002.12 (89914071..89914545) |
Secreted. Cell membrane.
PMID: 5595110 by Hilschmann N.; Chemical structure of 2 kappa-type Bence Jones proteins (Roy and Cum.).
PMID: 4893682 by Titani K., et al. The amino acid sequence of a kappa type Bence-Jones protein. 3. The complete sequence and the location of the disulfide bridges.