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- Table of Contents
Facts about Immunoglobulin kappa variable 2-29.
In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414).
Human | |
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Gene Name: | IGKV2-29 |
Uniprot: | A2NJV5 |
Entrez: | 28920 |
Belongs to: |
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No superfamily |
Immunoglobulin kappa variable 2-29
Mass (kDA):
13.085 kDA
Human | |
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Location: | 2p11.2 |
Sequence: | 2; NC_000002.12 (89234185..89234911, complement) |
Secreted. Cell membrane.
PMID: 8662073 by Atkinson M.J., et al. New alleles of IGKV genes A2 and A18 suggest significant human IGKV locus polymorphism.