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- Table of Contents
Facts about Immunoglobulin kappa variable 5-2.
In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414).
Human | |
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Gene Name: | IGKV5-2 |
Uniprot: | P06315 |
Entrez: | 28907 |
Belongs to: |
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No superfamily |
Immunoglobulin kappa variable 5-2
Mass (kDA):
12.728 kDA
Human | |
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Location: | 2p11.2 |
Sequence: | 2; NC_000002.12 (88897295..88897784) |
Secreted. Cell membrane.
PMID: 3925437 by Stavnezer J., et al. Aberrant recombination events in B cell lines derived from a kappa- deficient human.