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- Table of Contents
Facts about Immunoglobulin lambda variable 3-25.
In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414).
Human | |
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Gene Name: | IGLV3-25 |
Uniprot: | P01717 |
Entrez: | 28793 |
Belongs to: |
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No superfamily |
Immunoglobulin lambda variable 3-25
Mass (kDA):
12.011 kDA
Human | |
---|---|
Location: | 22q11.22 |
Sequence: | 22; NC_000022.11 (22686769..22687281) |
Secreted. Cell membrane.
PMID: 418804 by Lopez de Castro J.A., et al. Amino acid sequence of the variable region of the light (lambda) chain from human myeloma cryoimmunoglobulin IgG Hil.
PMID: 11872955 by Lefranc M.P.; Nomenclature of the human immunoglobulin lambda (IGL) genes.