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- Table of Contents
Designing a Western blot for IL15RA? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the IL15RA Western Blot Guide1 Citations
Facts about Interleukin-15 receptor subunit alpha.
Expression of distinct isoforms may alter or interfere with signal transduction. Isoform 5, isoform 6, isoform 7 and isoform 8 don't bind IL15.
| Human | |
|---|---|
| Gene Name: | IL15RA |
| Uniprot: | Q13261 |
| Entrez: | 3601 |

| Belongs to: |
|---|
| No superfamily |

CD215 antigen; CD215; IL15 R alpha; IL-15 R alpha; IL-15 receptor subunit alpha; IL-15R alpha; IL15RA; IL-15Ra; IL-15R-alpha; interleukin 15 receptor, alpha; interleukin-15 receptor subunit alpha; MGC104179
Mass (kDA):
28.233 kDA

| Human | |
|---|---|
| Location: | 10p15.1 |
| Sequence: | 10; NC_000010.11 (5948897..5978741, complement) |
Isoform 1, isoform 3, isoform 4, isoform 5, isoform 6, isoform 7, isoform 8 and isoform 9 are widely expressed. Expressed in fetal brain with higher expression in the hippocampus and cerebellum than in cortex and thalamus. Higher levels of soluble sIL-15RA form in comparison with membrane-bound forms is present in all brain structures.
Membrane; Single-pass type I membrane protein. Nucleus membrane; Single-pass type I membrane protein. Cell surface. Mainly found associated with the nuclear membrane.; [Isoform 5]: Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein. Isoform 5, isoform 6, isoform 7 and isoform 8 are associated with endoplasmic reticulum, Golgi and cytoplasmic vesicles, but not with the nuclear membrane.; [Isoform 6]: End





PMID: 8530383 by Anderson D.M., et al. Functional characterization of the human interleukin-15 receptor alpha chain and close linkage of IL15RA and IL2RA genes.
PMID: 9110174 by Yu W., et al. Large-scale concatenation cDNA sequencing.
*More publications can be found for each product on its corresponding product page