INPP4B Antibodies

AND INPP4B ELISA kits, INPP4B Proteins

Many biological assays use antibodies to detect INPP4B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with INPP4B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop INPP4B antibodies...

We validate the specificity of these antibodies to INPP4B by testing them on tissues known to express INPP4B positively and negatively. Browse below to find the INPP4B antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for INPP4B? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the INPP4B Western Blot Guide

INPP4B Infographic by Boster Bio

All INPP4B Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-INPP4B/Type Ii 4 Phosphatase Rabbit Monoclonal Antibody

1 Citations

Western blot analysis of INPP4B using anti-INPP4B antibody (M06336)

Human, Mouse, Rat

Flow Cytometry, IHC, WB

$370
Cat # M06336
100 μl

INPP4B (NM_003866) Human Over-expression Lysate

INPP4B Human Over-expression Lysates NM_001101669

Human

$628
Cat # LS008821
20 µg, 100 µg

Anti-INPP4B Antibody Picoband®

Western blot analysis of INPP4B using anti-INPP4B antibody (A06336-1)

IHC analysis of INPP4B using anti-INPP4B antibody (A06336-1)

Human, Mouse

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A06336-1
100 μg/vial

INPP4B (NM_001101669) Human Recombinant Protein

Coomassie blue staining of purified INPP4B protein

$1249
Cat # PROTO15327
20 µg

INPP4B Overview

Facts about Inositol polyphosphate 4-phosphatase type II.

INPP4B 3D structure. Source: alphafold

Inositol polyphosphate 4-phosphatase type II (INPP4B)

Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4- trisphosphate and inositol 1,4-bisphosphate (Probable). Plays a role in the late stages of macropinocytosis by dephosphorylating phosphatidylinositol 3,4-bisphosphate in membrane ruffles (PubMed:24591580).

Gene Information

Human
Gene Name:	INPP4B
Uniprot:	O15327
Entrez:	8821

Family

Belongs to:

inositol 3,4-bisphosphate 4-phosphatase family

Alternative Names

inositol polyphosphate-4-phosphatase, type II, 105kDa; type II inositol-3,4-bisphosphate 4-phosphatase

Molecular Weight

Mass (kDA):
104.738 kDA

Genomic Context


Human

Location:	4q31.21
Sequence:	4; NC_000004.12 (142023160..142846535, complement)

Tissue Specificity

Widely expressed with highest levels occurring in the skeletal muscle and heart.

Diseases

Neoplasms
Malignant Neoplasms
Leukemia
Malignant Neoplasm Of Breast
Mammary Neoplasms
Malignant Neoplasm Of Ovary
Abnormal Degeneration
Malignant Neoplasm Of Prostate
Fracture Of First Cervical Vertebra
Teratoma
Malignant Neoplasm Of Larynx

Oculocerebrorenal Syndrome
Familial Aplasia Of The Vermis
Down Syndrome
Carcinoma
Insulin Resistance
Bone Marrow Hyperplasia

Pathways

Cell Proliferation
Dna Repair
Cell Adhesion
Osteoclast Differentiation
Response To Wounding
Cell Migration
Cellular Senescence
Immune Response
Endocytosis
Senescence
Glucose Homeostasis
Drug Resistance
Translation

Cell Motility
Cell Death
Cell Differentiation
Cell Growth
Meiosis I
Luteinization
Meiosis

PTMs

Phosphorylation

Dephosphorylation

Research Areas

Cytokine Research

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/INPP4B

References

PMID: 9295334 by Norris F.A., et al. The cDNA cloning and characterization of inositol polyphosphate 4- phosphatase type II. Evidence for conserved alternative splicing in the 4-phosphatase family.

PMID: 19647222 by Gewinner C., et al. Evidence that inositol polyphosphate 4-phosphatase type II is a tumor suppressor that inhibits PI3K signaling.