Irgm1 Antibodies

AND Irgm1 ELISA kits, Irgm1 Proteins

Many biological assays use antibodies to detect Irgm1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Irgm1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Irgm1 antibodies...

We validate the specificity of these antibodies to Irgm1 by testing them on tissues known to express Irgm1 positively and negatively. Browse below to find the Irgm1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Irgm1 Infographic by Boster Bio

All Irgm1 Products

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Anti-IRGM/Irgm1 Antibody Picoband®

Western blot analysis of IRGM/Irgm1 using anti-IRGM/Irgm1 antibody (A33515)

Mouse

ELISA, WB

$370
Cat # A33515
100 μg/vial

Human IRGM Recombinant Protein

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain

SDS-PAGE, Denatured

$250
Cat # PROTA1A4Y4
Starting from 20ug

Irgm1 Overview

Facts about Immunity-related GTPase family M protein 1.

Irgm1 3D structure. Source: alphafold

Immunity-related GTPase family M protein 1 (Irgm1)

Putative GTPase which is required for IFNG-mediated clearance of acute protozoan and bacterial infections. Functions in innate immune response likely through regulation of autophagy.

May regulate proinflammatory cytokine production and prevent endotoxemia upon infection. Required for macrophage motility and maybe also for adhesion.

Gene Information

Mouse
Gene Name:	Irgm1
Uniprot:	Q60766
Entrez:	15944

Family

Belongs to:

TRAFAC class dynamin-like GTPase superfamily

Alternative Names

Immunity-related GTPase family M protein 1

Molecular Weight

Mass (kDA):
46.552 kDA

Genomic Context


Mouse

Location:	11\|11 B1.2
Sequence:	11;

Tissue Specificity

Expressed in lung and primary macrophages.

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Irgm1

References

PMID: 7561525 by Sorace J.M., et al. Identification of an endotoxin and IFN-inducible cDNA: possible identification of a novel protein family.

PMID: 8702776 by Taylor G.A., et al. Identification of a novel GTPase, the inducibly expressed GTPase, that accumulates in response to interferon gamma.