IRS2 Antibodies

AND IRS2 ELISA kits, IRS2 Proteins

Many biological assays use antibodies to detect IRS2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IRS2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IRS2 antibodies...

We validate the specificity of these antibodies to IRS2 by testing them on tissues known to express IRS2 positively and negatively. Browse below to find the IRS2 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for IRS2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the IRS2 Western Blot Guide

IRS2 Infographic by Boster Bio

All IRS2 Products

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Specificity

Applications

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Anti-IRS2 Antibody Picoband®

1 Citations

Western blot analysis of IRS2 using anti-IRS2 antibody (A00805-2)

IHC analysis of IRS2 using anti-IRS2 antibody (A00805-2)

IF analysis of IRS2 using anti-IRS2 antibody (A00805-2)

Human

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A00805-2
100 μg/vial

Anti-IRS2 Antibody Picoband®

Western blot analysis of IRS2 using anti-IRS2 antibody (A00805-3)

IHC analysis of IRS2 using anti-IRS2 antibody (A00805-3)

Human, Mouse, Rat

ELISA, IHC, WB

$370
Cat # A00805-3
100 μg/vial

Anti-IRS2 Rabbit Monoclonal Antibody

Western blot analysis of IRS2 using anti-IRS2 antibody (M00805)

IHC analysis of IRS2 using anti-IRS2 antibody (M00805)

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M00805
100 μl/vial

IRS2 (NM_003749) Human Over-expression Lysate

Human

$960
Cat # LS008660
20 µg, 100 µg

Anti-IRS2 Antibody (C-term)

Fluorescent image of Hela cell stained with IRS2 Antibody (C-term)

Anti-IRS2 Antibody (C-term) at 1:1000 dilution + Hela whole cell lysateLysates/proteins at 20 µg per lane

Western blot analysis of anti-IRS2 Antibody (C-term) in 293 cell line lysates (35ug/lane)

Human

IF, IHC-P, WB

$299
Cat # A00805-1
80 µl

Anti-Insulin receptor substrate 2 IRS2 Antibody

Western blot analysis of extracts of various cell lines, using IRS2 antibody at 1:500 dilution

Immunofluorescence analysis of SH-SY5Y cells using IRS2 Rabbit pAb at dilution of 1:50

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A00805
100ul

IRS2 Overview

Facts about Insulin receptor substrate 2.

IRS2 3D structure. Source: alphafold

Insulin receptor substrate 2 (IRS2)

May mediate the control of various cellular processes by insulin. .

Gene Information

Human
Gene Name:	IRS2
Uniprot:	Q9Y4H2
Entrez:	8660

Family

Belongs to:

No superfamily

Alternative Names

insulin receptor substrate 2; IRS2; IRS-2

Molecular Weight

Mass (kDA):
137.334 kDA

Genomic Context


Human

Location:	13q34
Sequence:	13; NC_000013.11 (109752695..109786583, complement)

Subcellular Localizations

Cytoplasm, cytosol.

Diseases

Insulin Resistance
Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Obesity
Insulin Sensitivity
Malignant Neoplasms
Hyperinsulinism
Neoplasms
Hyperglycemia
Impaired Glucose Tolerance
Diabetes Mellitus, Experimental
Liver Carcinoma

Malignant Neoplasm Of Breast
Mammary Neoplasms
Inflammation
Janiceps
Carcinoma
Hyperplasia
Polycystic Ovary Syndrome

Interacting Proteins

PIK3R1
SIRT1
YWHAZ

Pathways

Secretion
Insulin Secretion
Glucose Homeostasis
Transport
Glucose Transport
Cell Proliferation
Pathogenesis
Cell Growth
Aging
Cell Cycle
Localization
Gluconeogenesis
Translation

Cell Migration
Hypersensitivity
Cell Death
Lactation
Energy Homeostasis
Rna Interference
Cell Motility

PTMs

Phosphorylation
Cleavage
Dephosphorylation
Ubiquitination
Oxidation
Reduction
Deacetylation

Acetylation
Methylation
Myristoylation
Amidation
Acylation
Nitration
Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IRS2

References

PMID: 9312143 by Ogihara T., et al. 14-3-3 protein binds to insulin receptor substrate-1, one of the binding sites of which is in the phosphotyrosine binding domain.

PMID: 10077005 by Vassen L., et al. Human insulin receptor substrate-2 (IRS-2) is a primary progesterone response gene.