This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Integrin beta-7.
It recognizes one or more domain names within the alternatively spliced CS-1 region of fibronectin. Interactions entails the tripeptide L-D-T in MADCAM1, and L-D-V in fibronectin.
Human | |
---|---|
Gene Name: | ITGB7 |
Uniprot: | P26010 |
Entrez: | 3695 |
Belongs to: |
---|
integrin beta chain family |
Gut homing receptor beta subunit; integrin beta 7 subunit; Integrin beta 7; integrin beta-7; integrin, beta 7; ITGB7
Mass (kDA):
86.903 kDA
Human | |
---|---|
Location: | 12q13.13 |
Sequence: | 12; NC_000012.12 (53191318..53207375, complement) |
Expressed in a variety of leukocyte lines.
Membrane; Single-pass type I membrane protein.
Anti-CD18/ITGB2 markers are made from human antibodies that are polyclonal to CD18. These markers, listed under the catalog name PA1124 are designed for interaction of Human cells. This marker is stable at -20degC for one year and six months when stored in the freezer. The sequence is specific to human cells, and can be used in cloning, qRT-PCR, RNAi, and other applications.
The human leukocytes that carry the ITGB7 gene are found. It is part the ald T cell-homing receptor family. Cloning the ITGB7 gene allows you to create a mouse ES line that expresses the entire ORF. This clone is purified using an ion-exchange column, and is shipped in a 2D barcoded Matrix tube. The ORF clone will be delivered in a linearized version to C57BL/6 embryonics stem cells. The targeted ES clones will be verified using Southern blots. The mice used for the experiments were six to twelve weeks old and were euthanized with CO2 inhalation or cervical dislocation.
Boster Bio ITGB7 marker is only compatible with templates containing RNA or cDNA. The PCR method amplifies the sample using 45 cycles of 95 degC for fifteen seconds and two x IQ SYBRGreen Supermix. The reaction must be repeated ten times with serial dilutions. The logarithm based on the number of copies of the target gene template is used for computing the Ct value.
The ITGA7 marker can be detected in many biological assays using antibodies. These antibodies can be monoclonal (or polyclonal) and react with Integrin Alpha-7 in a variety. Boster Bio creates antibodies against ITGA7 using rabbit and mouse models. This antibody can detect mRNAs containing Integrin alpha-7 or its beta-subunit, which is a primary laminin receptor on skeletal myoblasts, which facilitates its localization in laminin-rich websites.
The ITGB7 marker is a protein present in human cells that binds to the tyrosine kinase inhibitor cytokine receptor gamma-glutamyltransferase. ITGB7 protein can be found in many tissues including liver, kidneys, lung, and ovary. Antibodies that recognize ITGB7 can be used to study various diseases. This antibody is part the Picoband(tm), and has been tested in ELISA as well as WB applications. It can be stored at 20°C for 6 mois. This antibody reacts to both Human and Mouse protein. It also contains 5mg BSA to help in storage.
The ITGB7 marker can be used in many biological assays. This allows researchers to identify the mRNA they are interested in. This marker is either monoclonal of polyclonal, and can cause reactions in many animals. Boster Bio produces its ITGB7 antibodies by using rabbit and mice samples. ITGA7 is the primary receptor for laminin in skeletal myoblasts. It is found in the cell, which allows it to be localized in laminin-rich areas.
PMID: 2083230 by Yuan Q., et al. Cloning and sequence analysis of a novel beta 2-related integrin transcript from T lymphocytes: homology of integrin cysteine-rich repeats to domain III of laminin B chains.
PMID: 1777426 by Yuan Q., et al. Cloning and sequence analysis of a novel beta 2-related integrin transcript from T lymphocytes: homology of integrin cysteine-rich repeats to domain III of laminin B chains.