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- Table of Contents
Facts about Interferon-activable protein 204.
Inhibits the transcription of ribosomal RNA.
May inhibit DNA binding by UBTF.Inhibits cell growth via p53/TP53 and RB1- dependent and independent pathways. Acts as a coactivator of RUNX2 during osteogenesis.
| Mouse | |
|---|---|
| Gene Name: | Ifi204 |
| Uniprot: | P0DOV2 |
| Entrez: | 15951 |

| Belongs to: |
|---|
| HIN-200 family |

Ifi16; Ifi204 interferon activated gene 204; p204
Mass (kDA):
69.438 kDA

| Mouse | |
|---|---|
| Location: | 1 H3|1 80.63 cM |
| Sequence: | 1; |
Present in osteoblasts (at protein level).



PMID: 2477366 by Choubey D., et al. Interferons as gene activators. Indications for repeated gene duplication during the evolution of a cluster of interferon- activatable genes on murine chromosome 1.
PMID: 10329630 by Liu C.J., et al. The interferon-inducible nucleolar p204 protein binds the ribosomal RNA-specific UBF1 transcription factor and inhibits ribosomal RNA transcription.