Il6ra Antibodies

AND Il6ra ELISA kits, Il6ra Proteins

Many biological assays use antibodies to detect Il6ra, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Il6ra in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Il6ra antibodies...

We validate the specificity of these antibodies to Il6ra by testing them on tissues known to express Il6ra positively and negatively. Browse below to find the Il6ra antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Il6ra Infographic by Boster Bio

All Il6ra Products

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Specificity

Applications

Price

Anti-IL-6Ra/CD126 Reference Antibody (tocilizumab)

The purity of Anti-IL-6Ra/CD126 Reference Antibody (tocilizumab)is more than 95%

Human

ELISA, Flow Cytometry, Functional Assay, Kinetics

$486
Cat # M01425-2
100 μg

Anti-IL-6Ra / CD126 Reference Antibody (vobarilizumab)

The purity of Anti-IL-6Ra/CD126 Reference Antibody (vobarilizumab)is more than 99

Human

ELISA, Flow Cytometry, Functional Assay, Kinetics

$486
Cat # M00102-7
100 μg

Anti-IL-6Ra / CD126 Reference Antibody (sapelizumab)

The purity of Anti-IL-6Ra/CD126 Reference Antibody (sapelizumab)is more than 95%

Human

ELISA, Flow Cytometry, Functional Assay, Kinetics

$486
Cat # M01425-6
100 μg

Anti-IL-6Ra / CD126 Reference Antibody (APX007)

The purity of Anti-IL-6Ra/CD126 Reference Antibody (APX007)is more than 95%

Human

ELISA, Flow Cytometry, Functional Assay, Kinetics

$486
Cat # M01425-5
100 μg

Anti-IL-6Ra / CD126 Reference Antibody (levilimab)

The purity of Anti-IL-6Ra/CD126 Reference Antibody (levilimab)is more than 95%

Human

ELISA, Flow Cytometry, Functional Assay, Kinetics

$486
Cat # M01425-4
100 μg

Anti-IL-6Ra / CD126 Reference Antibody (sarilumab)

The purity of Anti-IL-6Ra/CD126 Reference Antibody (sarilumab)is more than 95%

Human

ELISA, Flow Cytometry, Functional Assay, Kinetics

$486
Cat # M01425-3
100 μg

Il6ra Overview

Facts about Interleukin-6 receptor subunit alpha.

Il6ra 3D structure. Source: alphafold

Interleukin-6 receptor subunit alpha (Il6ra)

Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal.

Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis.

Gene Information

Mouse
Gene Name:	Il6ra
Uniprot:	P22272
Entrez:	16194

Family

Belongs to:

type I cytokine receptor family

Alternative Names

CD126; gp80; IL-6 R alpha; IL6Q; IL6R alpha; IL-6R alpha; IL6R; IL-6R-1; IL6RA; IL-6Ra; IL6RQ; interleukin 6 receptor

Molecular Weight

Mass (kDA):
50.455 kDA

Genomic Context


Mouse

Location:	3 F1\|3 39.19 cM
Sequence:	3;

Diseases

Inflammation
Malignant Neoplasms
Rheumatoid Arthritis
Diabetes Mellitus
Arthritis
Neoplasms
Diabetes Mellitus, Non-insulin-dependent
Cardiovascular Diseases
Obesity
Dysequilibrium Syndrome
Carcinoma
Atherosclerosis
Liver Carcinoma

Inflammatory Response
Heart Diseases
Multiple Myeloma
Coronary Heart Disease
Cholangiocarcinoma
Periodontitis
Autoimmune Reaction

Pathways

Pathogenesis
Immune Response
Inflammatory Response
Cell Proliferation
Secretion
Cell Growth
Transport
Aging
Interleukin-6 Production
Cell Cycle
Innate Immune Response
Localization
Cytokine Production

Angiogenesis
Cell Activation
Cell Migration
Proteolysis
Tube Formation
Cytokine Secretion
Vasculogenesis

PTMs

Phosphorylation
Cleavage
Biotinylation

Citrullination
Dephosphorylation
Iodination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Il6ra

References

PMID: 2112585 by Sugita T., et al. Functional murine interleukin 6 receptor with the intracisternal A particle gene product at its cytoplasmic domain. Its possible role in plasmacytomagenesis.

PMID: 28265003 by Larsen J.V., et al. SorLA in Interleukin-6 Signaling and Turnover.