IRF2BP1 Antibodies

AND IRF2BP1 ELISA kits, IRF2BP1 Proteins

Many biological assays use antibodies to detect IRF2BP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IRF2BP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IRF2BP1 antibodies...

We validate the specificity of these antibodies to IRF2BP1 by testing them on tissues known to express IRF2BP1 positively and negatively. Browse below to find the IRF2BP1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for IRF2BP1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the IRF2BP1 IHC Guide

IRF2BP1 Infographic by Boster Bio

All IRF2BP1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-IRF2BP1 Antibody Picoband®

Western blot analysis of IRF2BP1 using anti-IRF2BP1 antibody (A11406-2)

IHC analysis of IRF2BP1 using anti-IRF2BP1 antibody (A11406-2)

+23

Human, Mouse, Rat

ELISA, Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # A11406-2
100 μg/vial

IRF2BP1 (NM_015649) Human Over-expression Lysate

Human

$628
Cat # LS026145
20 µg, 100 µg

IRF2BP1 Overview

Facts about Interferon regulatory factor 2-binding protein 1.

IRF2BP1 3D structure. Source: alphafold

Interferon regulatory factor 2-binding protein 1 (IRF2BP1)

Acts as a transcriptional corepressor in a IRF2- dependent manner; this repression isn't mediated by histone deacetylase activities. May act as an E3 ligase towards JDP2, enhancing its polyubiquitination.

Represses ATF2-dependent transcriptional activation. .

Gene Information

Human
Gene Name:	IRF2BP1
Uniprot:	Q8IU81
Entrez:	26145

Family

Belongs to:

IRF2BP family

Alternative Names

DKFZP434M154; interferon regulatory factor 2 binding protein 1; interferon regulatory factor 2-binding protein 1; IRF-2-binding protein 1; IRF2BP1; IRF-2BP1

Molecular Weight

Mass (kDA):
61.688 kDA

Genomic Context


Human

Location:	19q13.32
Sequence:	19; NC_000019.10 (45883608..45886141, complement)

Subcellular Localizations

Nucleus.

Diseases

Leukemia
Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Breast
Acute Promyelocytic Leukemia
Mammary Neoplasms

Interacting Proteins

JDP2

Pathways

Histone Deacetylation

PTMs

Phosphorylation

Deacetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IRF2BP1

References

PMID: 12799427 by Childs K.S., et al. Identification of novel co-repressor molecules for interferon regulatory factor-2.

PMID: 18671972 by Kimura M.; IRF2-binding protein-1 is a JDP2 ubiquitin ligase and an inhibitor of ATF2-dependent transcription.