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- Table of Contents
Facts about Kazrin.
The function in the nucleus is not known. .
Human | |
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Gene Name: | KAZN |
Uniprot: | Q674X7 |
Entrez: | 23254 |
Belongs to: |
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kazrin family |
DKFZp686D08115; FLJ10199; FLJ32593; FLJ43806; KAZ; KAZRIN; kazrin, periplakin interacting protein; KIAA1026FLJ43398; MGC126686; MGC142181
Mass (kDA):
86.351 kDA
Human | |
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Location: | 1p36.21 |
Sequence: | 1; NC_000001.11 (13893386..15118043) |
Isoform 2, isoform 3 and isoform 4 are expressed in several cell lines including keratinocytes and bladder and epidermoid carcinoma (at protein level). Isoform 2, isoform 3 and isoform 4 are expressed in hair follicle and interfollicular epidermis (at protein level).
Cytoplasm, cytoskeleton.; [Isoform 2]: Cytoplasm. Cell junction, desmosome. Nucleus. Observed at the apical plasma membrane of keratinocytes. Partially colocalizes with PPL and DP at desmosomes, and with PP at the interdesmosomal plasma membrane. Colocalizes with cortical actin-based membrane structures.; [Isoform 3]: Cytoplasm. Cell junction, desmosome. Nucleus. Observed at the apical plasma membrane of keratinocytes. Partially colocalizes with PPL and DP at desmosomes, and with PP at the interdesmosomal plasma membrane. Colocalizes with cortical actin-based membrane structures.; [Isoform 4]:
PMID: 15337775 by Groot K.R., et al. Kazrin, a novel periplakin-interacting protein associated with desmosomes and the keratinocyte plasma membrane.
PMID: 9853615 by Ueki N., et al. Selection system for genes encoding nuclear-targeted proteins.