KCNA7 Antibodies

AND KCNA7 ELISA kits, KCNA7 Proteins

Many biological assays use antibodies to detect KCNA7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KCNA7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KCNA7 antibodies...

We validate the specificity of these antibodies to KCNA7 by testing them on tissues known to express KCNA7 positively and negatively. Browse below to find the KCNA7 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KCNA7 Infographic by Boster Bio

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KCNA7 (NM_031886) Human Over-expression Lysate

Human

$960
Cat # LS003743
20 µg, 100 µg

KCNA7 Overview

Facts about Potassium voltage-gated channel subfamily A member 7.

KCNA7 3D structure. Source: alphafold

Potassium voltage-gated channel subfamily A member 7 (KCNA7)

Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient (By similarity).

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Gene Information

Human
Gene Name:	KCNA7
Uniprot:	Q96RP8
Entrez:	3743

Family

Belongs to:

potassium channel family

Alternative Names

HAK6; KV1.7; potassium voltage-gated channel subfamily A member 7; potassium voltage-gated channel, shaker-related subfamily, member 7; voltage-dependent potassium channel Kv1.7; voltage-gated potassium channel KCNA7; Voltage-gated potassium channel subunit Kv1.7

Molecular Weight

Mass (kDA):
50.559 kDA

Genomic Context


Human

Location:	19q13.33
Sequence:	19; NC_000019.10 (49067418..49072941, complement)

Tissue Specificity

Highly expressed in skeletal muscle, heart and kidney.

Subcellular Localizations

Membrane; Multi-pass membrane protein.

Diseases

Diabetes Mellitus, Non-insulin-dependent
Hypertrophy
Hypertensive Disease
Metabolic Diseases
Heart Diseases
Insulinoma
Atrophy
Pulmonary Hypertension

Diabetes Mellitus
Heart Block
Hypoglycemia

Pathways

Insulin Secretion
Localization
Secretion

PTMs

Glycoprotein

Lipoprotein

Palmitate

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KCNA7

References

PMID: 11368907 by Kashuba V.I., et al. Initial isolation and analysis of the human Kv1.7 (KCNA7) gene, a member of the voltage-gated potassium channel gene family.

PMID: 11896454 by Bardien-Kruger S., et al. Characterisation of the human voltage-gated potassium channel gene, KCNA7, a candidate gene for inherited cardiac disorders, and its exclusion as cause of progressive familial heart block I (PFHBI).