Potassium voltage-gated channel subfamily E member 1 (KCNE1)

Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the station complex.

Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 (PubMed:19219384). Assembled with KCNQ1/KVLQT1 is suggested to form the slowly activating delayed rectifier cardiac potassium (IKs) channel.