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We validate the specificity of these antibodies to KCNIP2 by testing them on tissues known to express KCNIP2 positively and negatively. Browse below to find the KCNIP2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.
If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.
Facts about Kv channel-interacting protein 2.
In vitro, modulates KCND2/Kv4.2 and KCND3/Kv4.
A-type potassium channel modulatory protein 2; cardiac voltage gated potassium channel modulatory subunit; Cardiac voltage-gated potassium channel modulatory subunit; DKFZp566L1246; KChIP2; KCHIP2Kv channel-interacting protein 2; Kv channel interacting protein 2; MGC17241; potassium channel interacting protein 2; Potassium channel-interacting protein 2
|Sequence:||10; NC_000010.11 (101825971..101843920, complement)|
Expressed in brain. Colocalizes with KCND2 in excitatory neurons including cortical and hippocampal CA1 pyramidal cells. Isoform 3 is expressed in heart and in umbilical vein endothelial cells. Not expressed in fetal heart.
[Isoform 1]: Cell membrane; Lipid-anchor. Detected on lipid rafts (By similarity).; [Isoform 2]: Cell membrane; Lipid-anchor.; [Isoform 6]: Cell membrane; Lipid-anchor.
The Boster Bio. How do you obtain a high-sensitivity ELISA kits? Steven Boster is a well-known name for his KCNIP2 protein marker. What do you know of Steven Boster and his KCNIP2 marker? Continue reading to learn more about Steven Boster's life and research. You can also get an ELISA kit against KCNIP2 here. In this article, I will tell you a little about Steven Boster, his research and His primary antibodies.
The KCNIP2 genome encodes a protein expressed in the brain. The KCNIP2 gene is expressed by many cells in the brain and is known to be a marker for the neurotransmitter acetylcholinesterase. Scientists are currently researching the possible use of this gene to treat Alzheimer’s disease. There are numerous possible uses for this gene.
KCNIP2 and nontargeting shRNAs were created using Invitrogen's design algorithms and the RNAi Consortium. The oligos were first placed with their respective sequences of shRNA for control. The pSM2 vector was then used to prepare a PCR primer set with 0.1 mg/ml p-phenylenediamine (PBS) at pH 9.0.
John Hebert, a doctor, has recently described the marker's role as a cause of heart failure in a paper. The nucleus is where the KChIP2 protein can be found in human hearts. Patients with end-stage heart disease have lower levels than those without the condition.
This study has some limitations. It was not sufficient to determine the exact role KChIP2 plays in heart disease. It is therefore necessary to conduct larger and more controlled studies to determine if KChIP2 has been downregulated in heart disease. It could be a sign of heart dysfunction, but it may not be downregulated in disease. If it does, it could have implications on cardiovascular research and disease therapy.