KIR2DL1 Antibodies

AND KIR2DL1 ELISA kits, KIR2DL1 Proteins

Many biological assays use antibodies to detect KIR2DL1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KIR2DL1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KIR2DL1 antibodies...

We validate the specificity of these antibodies to KIR2DL1 by testing them on tissues known to express KIR2DL1 positively and negatively. Browse below to find the KIR2DL1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KIR2DL1 Infographic by Boster Bio

All KIR2DL1 Products

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Anti-CD158a KIR2DL1 Antibody

4 Q&As

Western Blot (WB) analysis of NIH-3T3 cells using CD158a Polyclonal antibody

Western Blot (WB) analysis of 3T3 cells using CD158a Polyclonal antibody

Human

ELISA, WB

$399
Cat # A02724
100μl

Human KIR2DL1/CD158a Recombinant Protein

SDS-PAGE

$265
Cat # PROTP43626
Starting from 20ug

KIR2DL1 (NM_014218) Human Over-expression Lysate

Human

$628
Cat # LS003802
20 µg, 100 µg

Anti-KIR2DL1 / CD158a Reference Antibody (Innate patent anti-KIR2DL)

The purity of Anti-KIR2DL1/CD158a Reference Antibody (Innate patent anti-KIR2DL)is more than 95%

Cynomolgus monkey, Human

ELISA, Flow Cytometry, Functional Assay, Kinetics

$486
Cat # M02724
100 μg

KIR2DL1 Overview

Facts about Killer cell immunoglobulin-like receptor 2DL1.

KIR2DL1 3D structure. Source: alphafold

Killer cell immunoglobulin-like receptor 2DL1 (KIR2DL1)

Receptor on natural killer (NK) cells for some HLA-C alleles such as w4 and w6. Inhibits the activity of NK cells thus preventing cell lysis.

Gene Information

Human
Gene Name:	KIR2DL1
Uniprot:	P43626
Entrez:	3802

Family

Belongs to:

immunoglobulin superfamily

Alternative Names

CD158a; KIR2DL1/KIR2DS5

Molecular Weight

Mass (kDA):
38.505 kDA

Genomic Context


Human

Location:	19q13.42
Sequence:	19; NC_000019.10 (54769208..54784326)

Tissue Specificity

Expressed by NK cells.

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein.

Diseases

Neoplasms
Leukemia
Dysequilibrium Syndrome
Virus Diseases
Autoimmune Reaction
Hematologic Neoplasms
Myeloid Leukemia
Autoimmune Diseases
Malignant Neoplasms
Graft-vs-host Disease
Hiv Infections
Immunologic Deficiency Syndromes

Arthritis
Leukemia, Myelocytic, Acute
Infective Disorder
Myeloid Leukemia, Chronic
Acute Gvh Disease
Autoimmunity
Arthritis, Psoriatic

Interacting Proteins

HLA-C
HLA-C
HLA-C
HLA-C
HLA-C

HLA-C
HLA-C
PTPN6

Pathways

Pathogenesis
Cell Activation
Immune Response
Cytolysis
Secretion
Cell Recognition
Cytokine Production
Cytokine Secretion
Cell Differentiation
Antibody-dependent Cellular Cytotoxicity
Cell Proliferation
Cell Killing
Donor Selection

Demethylation
Rna Interference
Cell Adhesion
Dna Demethylation
Cell Maturation
Cytoskeleton Organization
T Cell Proliferation

PTMs

Phosphorylation
Demethylation

Glycosylation
Methylation

Palmitoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KIR2DL1

References

PMID: 7716543 by Colonna M., et al. Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells.

PMID: 7749980 by Wagtmann N., et al. Molecular clones of the p58 NK cell receptor reveal immunoglobulin- related molecules with diversity in both the extra- and intracellular domains.