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Krueppel-like factor 10 Antibodies
AND KLF10 ELISA kits, Krueppel-like factor 10 Proteins
Many biological assays use antibodies to detect Krueppel-like factor 10, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Krueppel-like factor 10 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Krueppel-like factor 10 antibodies...
Designing a Western blot for Krueppel-like factor 10? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the KLF10 Western Blot GuideKLF10 Infographic by Boster Bio
All KLF10 Products
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KLF10 Overview
Facts about Krueppel-like factor 10.
Krueppel-like factor 10 (KLF10)
Transcriptional repressor which binds to the consensus sequence 5'-GGTGTG-3'. Plays a role in the regulation of the circadian clock; binds to the GC box sequence in the promoter of the center clock component ARTNL/BMAL1 and represses its transcriptional activity.
Regulates the circadian expression of enzymes involved in lipogenesis, gluconeogenesis, and glycolysis in the liver. Represses the expression of PCK2, a rate-limiting step enzyme of gluconeogenesis (By similarity).
Gene Information
| Human | |
|---|---|
| Gene Name: | KLF10 |
| Uniprot: | Q13118 |
| Entrez: | 7071 |
Family
| Belongs to: |
|---|
| Sp1 C2H2-type zinc-finger protein family |
Alternative Names
EGRA; EGR-alpha; KLF10; Krueppel-like factor 10; Kruppel-like factor 10; TGFB inducible early growth response; TGFB-inducible early growth response protein 1; TIEG1; TIEG-1; TIEG1TIEG; Transforming growth factor-beta-inducible early growth response protein 1
Molecular Weight
Mass (kDA):
52.555 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 8q22.3 |
| Sequence: | 8; NC_000008.11 (102648777..102655725, complement) |
Subcellular Localizations
Nucleus.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Malignant Neoplasm Of Pancreas
- Malignant Neoplasm Of Breast
- Cell Transformation, Neoplastic
- Inflammation
- Hypertrophy
- Mammary Neoplasms
- Pancreatic Neoplasm
- Adenocarcinoma
- Atherosclerosis
- Neoplasm Metastasis
Interacting Proteins
- SP1
Pathways
- Cell Proliferation
- Cell Cycle
- Cell Growth
- Cell Death
- Cell Differentiation
- Localization
- Pathogenesis
- Osteoclast Differentiation
- Cell Cycle Arrest
- Regulation Of Gene Expression
- Translation
- G1 Phase
- Methylation
PTMs
- Phosphorylation
- Methylation
- Demethylation
Research Areas
- Cell Cycle and Replication
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KLF10
bosterbio.com/bosterbio-gene-info-cards/KLF10
References
PMID: 8584037 by Blok L.J., et al. Characterization of an early growth response gene, which encodes a zinc finger transcription factor, potentially involved in cell cycle regulation.
PMID: 8532536 by Subramaniam M., et al. Identification of a novel TGF-beta-regulated gene encoding a putative zinc finger protein in human osteoblasts.
1 Publications of Boster Krueppel-like factor 10 Antibodies & ELISA Kits
- PubMed ID: 32156482, Zheng L,Lu H,Li H,Xu X,Wang D.KLF10 is upregulated in osteoarthritis and inhibit...
*More publications can be found for each product on its corresponding product page