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- Table of Contents
Facts about Kallikrein-10.
Human | |
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Gene Name: | KLK10 |
Uniprot: | O43240 |
Entrez: | 5655 |
Belongs to: |
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peptidase S1 family |
breast normal epithelial cell associated serine protease; EC 3.4.21; EC 3.4.21.-; EC 3.4.21.74; Kallikrein 10; kallikrein-related peptidase 10; KLK10; NES1; NES1kallikrein-10; Normal epithelial cell-specific 1; Protease serine-like 1; PRSSL1protease, serine-like, 1
Mass (kDA):
30.17 kDA
Human | |
---|---|
Location: | 19q13.41 |
Sequence: | 19; NC_000019.10 (51012739..51020175, complement) |
Expressed in breast, ovary and prostate.
Secreted.
High-affinity primary antibodies are required to test the KLK10 MAb. Boster Bio offers high-affinity antibodies for this target protein, but there are several factors to consider before choosing one. Learn how to optimize your antibody to get the best results. We'll also be discussing the various flow options available for this marker.
Boster Bio may be able to provide the right reagent depending on your needs. Sanbio can assist you with custom services as well as BeNeLux deliveries. This biotech company also offers high affinity primary antibodies against KLK10 marker. For more information about Boster Bio's KLK10 marker markers, contact them today.
Boster offers a Recombinant Immunogen to determine the specificity a specific antibody. Its high affinity antibodies recognize proteins that have been expressed on human cells. These antibodies are available in ELISA kit form or for IHC analysis. Boster's reagents were designed by top immunogen developers and deliver high-sensitivity results with very high levels of sensitivity.
The purity of mat-KLK9 was confirmed using Coomassie and silver staining. KLK9 expression was confirmed by several chromatographic fractions. The amount of matKLK9 was determined using the chromatographic fractions by performing a selective reaction monitoring analysis. The results of this assay are presented as arbitrary fluorescence units (AFUs).
High-affinity secondary antibodies against KLK9 have been created by the recombinant KLK9 in a sandwich ELISA. To determine which mAbs produce the best signal, a number of biological samples were tested using these antibodies. This method is also widely used in clinical trials and diagnostics.
Boster Bio provides high-affinity primary antibodies against the KLK10 marker to detect tumor cells. This marker has been recognized as a key indicator for cancer in many types including gastrointestinal tumors. The development of different cancers is also linked to this protein. KLK10 is a great biomarker to use in clinical trials.
The production of the biotinylated anti-KLK9 antibody is based on somatic cell fusion. After initial screening 18 hybridomas were identified and expanded in serumless media. Purified IgGs were tested against mat-KLK9 to determine the affinity of the antibodies. The 28ED436-mAb had the highest binding signals, followed 16 monoclonal mice antibodies.
PMID: 8764136 by Liu X.-L., et al. Identification of a novel serine protease-like gene, the expression of which is down-regulated during breast cancer progression.
PMID: 9647736 by Luo L.-Y., et al. Structural characterization and mapping of the normal epithelial cell-specific 1 gene.