LETMD1 Antibodies

AND LETMD1 ELISA kits, LETMD1 Proteins

Many biological assays use antibodies to detect LETMD1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LETMD1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LETMD1 antibodies...

We validate the specificity of these antibodies to LETMD1 by testing them on tissues known to express LETMD1 positively and negatively. Browse below to find the LETMD1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LETMD1 Infographic by Boster Bio

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LETMD1 (NM_015416) Human Over-expression Lysate

Human

$628
Cat # LS025875
20 µg, 100 µg

LETMD1 Overview

Facts about LETM1 domain-containing protein 1.

LETMD1 3D structure. Source: alphafold

LETM1 domain-containing protein 1 (LETMD1)

Involved in tumorigenesis and might be a negative regulator of the p53/TP53. .

Gene Information

Human
Gene Name:	LETMD1
Uniprot:	Q6P1Q0
Entrez:	25875

Family

Belongs to:

No superfamily

Alternative Names

1110019O13Rik; Cervical cancer 1 proto-oncogene protein p40; cervical cancer 1 protooncogene; Cervical cancer proto-oncogene 2 protein; DKFZp586A011; HCCR1; HCCR-1; HCCR-2; HCRR-2; LETM1 domain containing 1; LETM1 domain-containing protein 1; regulator of TP53

Molecular Weight

Mass (kDA):
41.79 kDA

Genomic Context


Human

Location:	12q13.12
Sequence:	12; NC_000012.12 (51048220..51068958)

Subcellular Localizations

Mitochondrion outer membrane; Single-pass membrane protein.

Diseases

Malignant Neoplasms
Neoplasms
Malignant Tumor Of Cervix
Carcinoma
Liver Carcinoma
Cell Transformation, Neoplastic
Liver Neoplasms
Uterine Cervical Neoplasm
Malignant Neoplasm Of Breast
Malignant Paraganglionic Neoplasm
Neoplasm Metastasis
Mammary Neoplasms
Liver Cirrhosis

Tumor Progression
Hepatitis
Metaplastic Cell Transformation
Liver Diseases
Metastatic Malignant Neoplasm To The Lymph Node
Hepatitis, Chronic
Malignant Neoplasm Of Liver

Interacting Proteins

REEP5

Pathways

Cell Division
Cell Proliferation
Cell Migration
Rna Interference
Secretion
Transdifferentiation

Oncogenesis

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LETMD1

References

PMID: 12879013 by Ko J., et al. Identification and differential expression of novel human cervical cancer oncogene HCCR-2 in human cancers and its involvement in p53 stabilization.

PMID: 18045496 by Cho G.W., et al. HCCR-1, a novel oncogene, encodes a mitochondrial outer membrane protein and suppresses the UVC-induced apoptosis.