Lengsin Antibodies

AND LGSN ELISA kits, Lengsin Proteins

Many biological assays use antibodies to detect Lengsin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Lengsin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Lengsin antibodies...

We validate the specificity of these antibodies to Lengsin by testing them on tissues known to express LGSN positively and negatively. Browse below to find the LGSN antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LGSN Infographic by Boster Bio

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LGSN (NM_016571) Human Over-expression Lysate

Human

$960
Cat # LS051557
20 µg, 100 µg

LGSN Overview

Facts about Lengsin.

LGSN 3D structure. Source: alphafold

Lengsin (LGSN)

May act as a component of the cytoskeleton or as a chaperone for the reorganization of intermediate filament proteins during terminal differentiation in the lens. Doesn't seem to have enzymatic activity (By similarity).

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Gene Information

Human
Gene Name:	LGSN
Uniprot:	Q5TDP6
Entrez:	51557

Family

Belongs to:

glutamine synthetase family

Alternative Names

GLULD1; glutamate-ammonia ligase (glutamine synthase) domain containing 1; glutamate-ammonia ligase (glutamine synthetase) domain containing 1; Glutamate-ammonia ligase domain-containing protein 1; lengsin; lengsin, lens protein with glutamine synthetase domain; Lens glutamine synthase-like; LGSMGC163240; MGC163238

Molecular Weight

Mass (kDA):
57.278 kDA

Genomic Context


Human

Location:	6q12
Sequence:	6; NC_000006.12 (63275951..63567921, complement)

Tissue Specificity

Abundantly expressed in lens.

Diseases

Malignant Neoplasm Of Lung
Carcinoma
Malignant Neoplasms
Adenocarcinoma
Lung Neoplasms
Gaucher Disease
Retinal Dystrophies
Acute Myelomonocytic Leukemia
Retinal Degeneration
Myelomonocytic Leukemia
Melanoma
Malignant Neoplasm Of Breast

Mucopolysaccharidosis, Mps-iv-a
Mucopolysaccharidoses
Carcinoma, Large Cell
Colorectal Cancer
Comatose
Malignant Squamous Cell Neoplasm

Pathways

Cell Proliferation
Cell Death
T Cell Proliferation
Cytokine Secretion
Interleukin-2 Production
Innervation

Secretion

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LGSN

References

PMID: 17010935 by Grassi F., et al. Structural and functional properties of lengsin, a pseudo-glutamine synthetase in the transparent human lens.

PMID: 12107413 by Wistow G., et al. Expressed sequence tag analysis of adult human lens for the NEIBank project: over 2000 non-redundant transcripts, novel genes and splice variants.