LILRA3 Antibodies

AND LILRA3 ELISA kits, LILRA3 Proteins

Many biological assays use antibodies to detect LILRA3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LILRA3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LILRA3 antibodies...

We validate the specificity of these antibodies to LILRA3 by testing them on tissues known to express LILRA3 positively and negatively. Browse below to find the LILRA3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LILRA3 Infographic by Boster Bio

All LILRA3 Products

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Product

Figures

Specificity

Applications

Price

Human LILRA3/CD85e ELISA Kit PicoKine®

8 Q&As

Human

ELISA

$750
Cat # EK2113
96 wells/kit, with removable strips.

Anti-LILRA3 Antibody (C-term)

LILRA3 Antibody (C-term) western blot analysis in Daudi,HL-60,Raji and Ramos cell line lysates (35ug/lane)

Human

$299
Cat # A06300
80 µl

Human LILRA3/CD85e Recombinant Protein

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain

Human

SDS-PAGE

$275
Cat # PROTOQ8N6C8
starting from 10ug

LILRA3 Overview

Facts about Leukocyte immunoglobulin-like receptor subfamily A member 3.

LILRA3 3D structure. Source: alphafold

Leukocyte immunoglobulin-like receptor subfamily A member 3 (LILRA3)

Acts as soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2.

Binds with high affinity to the surface of monocytes, leading to abolish LPS- induced TNF-alpha production by monocytes. .

Gene Information

Human
Gene Name:	LILRA3
Uniprot:	Q8N6C8
Entrez:	11026

Family

Belongs to:

No superfamily

Alternative Names

CD85 antigen-like family member E; CD85e antigen; CD85e; HM31; HM43; ILT6; ILT-6; ILT6CD85e; Immunoglobulin-like transcript 6; leucocyte immunoglobulin-like receptor; Leukocyte immunoglobulin-like receptor 4; leukocyte immunoglobulin-like receptor A3; leukocyte immunoglobulin-like receptor subfamily A member 3; leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member3; LILRA3; LIR4; LIR4CD85E; LIR-4HM43e3; Monocyte inhibitory receptor HM43/HM31

Molecular Weight

Mass (kDA):
47.472 kDA

Genomic Context


Human

Location:	19q13.4
Sequence:	19; NT_187693.1 (270964..275379, complement)

Tissue Specificity

Detected in B-cells, and at lower levels in natural killer (NK) cells. Detected in peripheral blood monocytes and lung.

Subcellular Localizations

Secreted.

Diseases

Sclerosis
Dysequilibrium Syndrome
Multiple Sclerosis
Sjogren's Syndrome
Arthritis
Rheumatoid Arthritis
Infective Disorder
Autoimmune Reaction
Autoimmunity
Polyneuropathy
Keratoconjunctivitis Sicca
Degenerative Polyarthritis

Inflammatory Response
Sicca Syndrome
Malignant Neoplasms
Neoplasms
Celiac Disease
Gout
Abnormal Degeneration

Pathways

Immune Response
Pathogenesis
Tolerance Induction
Inflammatory Response

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LILRA3

References

PMID: 9278324 by Arm J.P., et al. Molecular identification of a novel family of human Ig superfamily members that possess immunoreceptor tyrosine-based inhibition motifs and homology to the mouse gp49B1 inhibitory receptor.

PMID: 9548455 by Borges L., et al. A family of human lymphoid and myeloid Ig-like receptors, some of which bind to MHC class I molecules.