LIM2 Antibodies

AND LIM2 ELISA kits, LIM2 Proteins

Many biological assays use antibodies to detect LIM2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LIM2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LIM2 antibodies...

We validate the specificity of these antibodies to LIM2 by testing them on tissues known to express LIM2 positively and negatively. Browse below to find the LIM2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LIM2 Infographic by Boster Bio

All LIM2 Products

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Specificity

Applications

Price

Anti-LIM2 Antibody

Western blot analysis of extracts of various cell lines, using LIM2 antibody at 1:1000 dilution

Human, Mouse, Rat

$405
Cat # A06483
100ul

LIM2 (NM_030657) Human Over-expression Lysate

LIM2 Human Over-expression Lysates NM_001161748

Human

$628
Cat # LS003982
20 µg, 100 µg

LIM2 Overview

Facts about Lens fiber membrane intrinsic protein.

LIM2 3D structure. Source: alphafold

Lens fiber membrane intrinsic protein (LIM2)

Current in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it can contribute to cell junctional organization. Acts as a receptor for calmodulin.

May play an essential role in both lens growth and cataractogenesis. .

Gene Information

Human
Gene Name:	LIM2
Uniprot:	P55344
Entrez:	3982

Family

Belongs to:

PMP-22/EMP/MP20 family

Alternative Names

lens fiber membrane intrinsic protein; lens intrinsic membrane protein 2, 19kDa; MP17; MP18; MP19lens intrinsic membrane protein 2 (19kD); MP20

Molecular Weight

Mass (kDA):
19.674 kDA

Genomic Context


Human

Location:	19q13.41
Sequence:	19; NC_000019.10 (51379909..51387974, complement)

Tissue Specificity

Eye lens specific.

Subcellular Localizations

Membrane; Multi-pass membrane protein.

Diseases

Cataract
Tissue Adhesions
Microphthalmos
Nervousness
Congenital Lamellar Cataract
Mature Cataract
Cholangiocarcinoma
Acute Erythroblastic Leukemia
Mastitis
Posttransfusion Purpura
Cataract, Congenital, Cerulean Type 1

Senile Cataract
Eye Diseases, Hereditary
Steroid Sulfatase Deficiency Disease
Lens Opacities
Aqueous Humor Disorders
Cytogenetic Abnormality

Pathways

Localization
Cell Differentiation
Cell Adhesion
Transport
Cell Proliferation
Pathogenesis
Neurogenesis
Cell Fate Determination
Cell Motility
Cell Growth
Regulation Of Protein Localization
Cell Migration
Electron Transport

Chemotaxis
Reverse Transcription
System Development
Central Nervous System Development
Eye Development
Translational Termination
Cell Development

PTMs

Phosphorylation

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LIM2

References

PMID: 8137630 by Church R.L., et al. The human lens fiber-cell intrinsic membrane protein MP19 gene: isolation and sequence analysis.

PMID: 12107413 by Wistow G., et al. Expressed sequence tag analysis of adult human lens for the NEIBank project: over 2000 non-redundant transcripts, novel genes and splice variants.