LIMS1 Antibodies

AND LIMS1 ELISA kits, LIMS1 Proteins

Many biological assays use antibodies to detect LIMS1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LIMS1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LIMS1 antibodies...

We validate the specificity of these antibodies to LIMS1 by testing them on tissues known to express LIMS1 positively and negatively. Browse below to find the LIMS1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LIMS1 Infographic by Boster Bio

All LIMS1 Products

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Anti-Pinch-1 LIMS1 Monoclonal Antibody

13 Q&As

Western Blot (WB) analysis using Pinch-1 Monoclonal antibody against A549 (1), Jurkat (2), and HeLa (3) cell lysate

Flow cytometric (FCM) analysis of HeLa cells using Pinch-1 Monoclonal antibody (blue) and negative control (red)

Immunofluorescence (IF) analysis of HepG2 cells using Pinch-1 Monoclonal antibody (green)

Human

ELISA, Flow Cytometry, IF, WB

$399
Cat # A04072
100μl

Anti-LIMS1 Antibody

Western blot analysis of extracts of HepG2 cells, using LIMS1 antibody at 1:1000 dilution

Immunofluorescence analysis of MCF7 cells using LIMS1 antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A04072-1
100ul

Anti-LIMS1 Antibody Picoband®

Western blot analysis of LIMS1 using anti-LIMS1 antibody (A04072-2)

Human, Mouse, Rat

ELISA, WB

$370
Cat # A04072-2
100 µg/vial

Anti-Zebrafish LIMS1 Antibody Picoband®

Western blot analysis of LIMS1 using anti-LIMS1 antibody (AZA0A8M9QHP1)

IHC analysis of LIMS1 using anti-LIMS1 antibody (AZA0A8M9QHP1)

Zebrafish

IHC, WB

$470
Cat # AZA0A8M9QHP1
100 μg/vial

LIMS1 Overview

Facts about LIM and senescent cell antigen-like-containing domain protein 1.

LIMS1 3D structure. Source: alphafold

LIM and senescent cell antigen-like-containing domain protein 1 (LIMS1)

Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complicated to cell surface receptor tyrosine kinases and growth factor receptors. Involved in the regulation of cell survival, cell proliferation and cell differentiation.

Gene Information

Human
Gene Name:	LIMS1
Uniprot:	P48059
Entrez:	3987

Family

Belongs to:

No superfamily

Alternative Names

LIM and senescent cell antigen-like domains 1; LIM and senescent cell antigen-like-containing domain protein 1; LIMS1; PINCH1; PINCH-1; PINCHPINCH1Particularly interesting new Cys-His protein 1; Renal carcinoma antigen NY-REN-48

Molecular Weight

Mass (kDA):
37.251 kDA

Genomic Context


Human

Location:	2q12.3
Sequence:	2; NC_000002.12 (108533671..108687246)

Subcellular Localizations

Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side.

Diseases

Tissue Adhesions
Neoplasms
Malignant Neoplasms
Carcinoma
Neoplasm Metastasis
Adenocarcinoma
Colorectal Cancer
Cell Invasion
Colorectal Neoplasms
Malignant Paraganglionic Neoplasm
Lymphatic Metastasis
Malignant Neoplasm Of Breast
Tumor Angiogenesis

Tumor Progression
Hyperplasia
Fibrosis
Heart Diseases
Inflammation
Cell Transformation, Neoplastic
Malignant Squamous Cell Neoplasm

Interacting Proteins

Hoxa1
ILK
Ilk
NCK2
RSU1

Pathways

Cell Adhesion
Localization
Cell Migration
Cell Proliferation
Cell Growth
Cell Cycle
Intracellular Signal Transduction
Cell Death
Angiogenesis
Nuclear Export
Focal Adhesion Assembly
Cell-cell Adhesion
Regulation Of Cell Adhesion

Pathogenesis
Rna Interference
Hair Follicle Morphogenesis
Adherens Junction Assembly
Chemokine Production
Immune Response
Lymphangiogenesis

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LIMS1

References

PMID: 7517666 by Rearden A.; A new LIM protein containing an autoepitope homologous to 'senescent cell antigen'.

PMID: 9843575 by Tu Y., et al. Nck-2, a novel Src homology2/3-containing adaptor protein that interacts with the LIM-only protein PINCH and components of growth factor receptor kinase-signaling pathways.