LLGL2 Antibodies

AND LLGL2 ELISA kits, LLGL2 Proteins

Many biological assays use antibodies to detect LLGL2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LLGL2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LLGL2 antibodies...

We validate the specificity of these antibodies to LLGL2 by testing them on tissues known to express LLGL2 positively and negatively. Browse below to find the LLGL2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LLGL2 Infographic by Boster Bio

All LLGL2 Products

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Specificity

Applications

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Anti-LLGL2 Antibody

Western blot analysis of extracts of various cell lines, using LLGL2 antibody at 1:1000 dilution

Immunofluorescence analysis of U2OS cells using LLGL2 antibody at dilution of 1:100

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A08503
100ul

LLGL2 (NM_001031803) Human Recombinant Protein

Coomassie blue staining of purified LLGL2 protein

$1062
Cat # PROTQ6P1M3
20 µg

LLGL2 (NM_001015002) Human Over-expression Lysate

LLGL2 Human Over-expression Lysates NM_001015002

Human

$628
Cat # LS003993
20 µg, 100 µg

Anti-LLGL2 Antibody Picoband®

Western blot analysis of LLGL2 using anti-LLGL2 antibody (A08503-1)

Flow Cytometry analysis of HepG2 cells using anti-LLGL2 antibody (A08503-1)

Human

ELISA, Flow Cytometry, WB

$370
Cat # A08503-1
100 µg/vial

LLGL2 Overview

Facts about LLGL scribble cell polarity complex component 2.

LLGL2 3D structure. Source: alphafold

LLGL scribble cell polarity complex component 2 (LLGL2)

Part of a complex with GPSM2/LGN, PRKCI/aPKC and PARD6B/Par-6, which might ensure the right organization and orientation of bipolar spindles for normal cell division. This complex plays roles in the first phase of the establishment of epithelial cell polarity.

Gene Information

Human
Gene Name:	LLGL2
Uniprot:	Q6P1M3
Entrez:	3993

Family

Belongs to:

WD repeat L(2)GL family

Alternative Names

HGLlethal giant larvae (Drosophila) homolog 2; human giant larvae homolog; lethal giant larvae homolog 2 (Drosophila); lethal(2) giant larvae protein homolog 2; LGL2

Molecular Weight

Mass (kDA):
113.448 kDA

Genomic Context


Human

Location:	17q25.1
Sequence:	17; NC_000017.11 (75525080..75575209)

Subcellular Localizations

Cytoplasm. Localized in the perinuclear structure and faintly at the cell-cell contacts sites in the interphase. Localized at the cell periphery during metaphase. Cortical localization in mitotic cells. Found in the lateral region of polarized epithelial cells.

Diseases

Neoplasms
Ischemic Stroke
Brain Ischemia
Cerebrovascular Accident
Cell Invasion
Cell Transformation, Neoplastic
Tumor Progression
Severe Congenital Neutropenia
Leukemia, Myelocytic, Acute
Carcinoid Tumor

Myeloid Leukemia
Leukemia
Germ Cell Tumor
Dysequilibrium Syndrome

Pathways

Pathogenesis

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LLGL2

References

PMID: 15632202 by Yasumi M., et al. Direct binding of Lgl2 to LGN during mitosis and its requirement for normal cell division.

PMID: 12725730 by Yamanaka T., et al. Mammalian Lgl forms a protein complex with PAR-6 and aPKC independently of PAR-3 to regulate epithelial cell polarity.