LRBA Antibodies

AND LRBA ELISA kits, LRBA Proteins

Many biological assays use antibodies to detect LRBA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LRBA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LRBA antibodies...

We validate the specificity of these antibodies to LRBA by testing them on tissues known to express LRBA positively and negatively. Browse below to find the LRBA antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for LRBA? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the LRBA IHC Guide

LRBA Infographic by Boster Bio

All LRBA Products

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Anti-LRBA Antibody

Immunohistochemical analysis of paraffin-embedded human tonsil

Human, Mouse

IF, IHC

$380
Cat # A04947
100ul

LRBA Overview

Facts about Lipopolysaccharide-responsive and beige-like anchor protein.

Lipopolysaccharide-responsive and beige-like anchor protein (LRBA)

Might be involved in coupling signal transduction and vesicle trafficking to enable polarized secretion and/or membrane deposition of immune effector molecules. .

Gene Information

Human
Gene Name:	LRBA
Uniprot:	P50851
Entrez:	987

Family

Belongs to:

No superfamily

Alternative Names

CDC4L; CDC4-like protein; DKFZp686A09128; DKFZp686K03100; FLJ16600; LAB300; LBA; lipopolysaccharide-responsive and beige-like anchor protein; LPS-responsive vesicle trafficking, beach and anchor containing; MGC72098; vesicle trafficking, beach and anchor containing

Molecular Weight

Mass (kDA):
319.108 kDA

Genomic Context


Human

Location:	4q31.3
Sequence:	4; NC_000004.12 (150264435..151015727, complement)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Cell membrane; Single-pass membrane protein. Endoplasmic reticulum. Golgi apparatus, trans-Golgi network. Lysosome.

Diseases

Immunologic Deficiency Syndromes
Autoimmunity
Malignant Neoplasms
Hypogammaglobulinemia
Neoplasms
Mammary Neoplasms
Chediak-higashi Syndrome
Hypotension Adverse Event
Amaurosis
Malignant Neoplasm Of Breast
Inflammatory Bowel Diseases

Intestinal Diseases
Neoplasms, Hormone-dependent
Severe Combined Immunodeficiency
Primary Immune Deficiency Disorder
Lymphoma

Pathways

Endocytosis
Secretion
Transport
Cell Activation
Intracellular Transport
Cell Development
B Cell Activation
Immunoglobulin Secretion
Reverse Transcription

Cell Growth
Pathogenesis
Rna Interference
Autophagy

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LRBA

References

PMID: 11254716 by Wang J.-W., et al. Identification of a novel lipopolysaccharide-inducible gene with key features of both A kinase anchor proteins and chs1/beige proteins.

PMID: 12160729 by Dyomin V.G., et al. BCL8 is a novel, evolutionarily conserved human gene family encoding proteins with presumptive protein kinase A anchoring function.