LRRTM2 Antibodies

AND LRRTM2 ELISA kits, LRRTM2 Proteins

Many biological assays use antibodies to detect LRRTM2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LRRTM2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LRRTM2 antibodies...

We validate the specificity of these antibodies to LRRTM2 by testing them on tissues known to express LRRTM2 positively and negatively. Browse below to find the LRRTM2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LRRTM2 Infographic by Boster Bio

All LRRTM2 Products

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Anti-LRRTM2 Antibody

Western blot analysis of LRRTM2 in SK-N-SH cell lysate with LRRTM2 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide

Immunohistochemistry of LRRTM2 in human brain tissue with LRRTM2 antibody at 2

Immunofluorescence of LRRTM2 in human brain tissue with LRRTM2 antibody at 20 μg/mL

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$481
Cat # A11486
0.1 mg

LRRTM2 Overview

Facts about Leucine-rich repeat transmembrane neuronal protein 2.

LRRTM2 3D structure. Source: alphafold

Leucine-rich repeat transmembrane neuronal protein 2 (LRRTM2)

Involved in the development and maintenance of excitatory synapse in the vertebrate nervous system. Regulates surface expression of AMPA receptors and educates the development of functional glutamate release sites.

Acts as a ligand for the presynaptic receptors NRXN1-A and NRXN1-B (By similarity). .

Gene Information

Human
Gene Name:	LRRTM2
Uniprot:	O43300
Entrez:	26045

Family

Belongs to:

LRRTM family

Alternative Names

leucine-rich repeat transmembrane neuronal protein 2; leucine rich repeat transmembrane neuronal 2; LRRN2; LRRTM2

Molecular Weight

Mass (kDA):
59.076 kDA

Genomic Context


Human

Location:	5q31.2
Sequence:	5; NC_000005.10 (138868921..138875335, complement)

Tissue Specificity

Expressed in neuronal tissues.

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic cell membrane; Single-pass type I membrane protein. Localized to excitatory synapses.

Diseases

Schizophrenia
Tissue Adhesions
Autistic Disorder
Nervousness
Autism Spectrum Disorders
Child Development Disorders, Pervasive
Language Development Disorders

Language Delays

Pathways

Synapse Maturation
Cell Adhesion
Synapse Assembly
Synaptic Transmission
Cognition
Pathogenesis

PTMs

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LRRTM2

References

PMID: 12676565 by Lauren J., et al. A novel gene family encoding leucine-rich repeat transmembrane proteins differentially expressed in the nervous system.