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- Table of Contents
Facts about Lymphocyte antigen 75.
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Human | |
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Gene Name: | LY75 |
Uniprot: | O60449 |
Entrez: | 4065 |
Belongs to: |
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No superfamily |
CD205; DEC205; DEC-205; Ly75
Mass (kDA):
198.311 kDA
Human | |
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Location: | 2q24.2 |
Sequence: | 2; NC_000002.12 (159803355..159904756, complement) |
Expressed in spleen, thymus, colon and peripheral blood lymphocytes. Detected in myeloid and B-lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells.
Membrane; Single-pass type I membrane protein.
PMID: 9862343 by McKay P.F., et al. The gp200-MR6 molecule which is functionally associated with the IL-4 receptor modulates B cell phenotype and is a novel member of the human macrophage mannose receptor family.
PMID: 9553150 by Kato M., et al. cDNA cloning of human DEC-205, a putative antigen-uptake receptor on dendritic cells.