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- Table of Contents
Transcription factor MafG Antibodies
AND MAFG ELISA kits, Transcription factor MafG Proteins
Many biological assays use antibodies to detect Transcription factor MafG, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Transcription factor MafG in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Transcription factor MafG antibodies...
Designing a Western blot for Transcription factor MafG? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the MAFG Western Blot GuideMAFG Infographic by Boster Bio
All MAFG Products
Product
Figures
Specificity
Applications
Price
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M03364
100 μl
Cat # M03364
100 μl
MAFG Overview
Facts about Transcription factor MafG.
Transcription factor MafG (MAFG)
Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves (PubMed:11154691). However, they appear to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins, such as NFE2, NFE2L1 and NFE2L2, and recruiting them to particular DNA-binding sites (PubMed:8932385, PubMed:9421508, PubMed:11154691).
Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NFE2L2 transcription factor (PubMed:11154691). Transcription factor, part of erythroid-specific transcription factor NFE2L2 (PubMed:11154691).
Gene Information
| Human | |
|---|---|
| Gene Name: | MAFG |
| Uniprot: | O15525 |
| Entrez: | 4097 |
Family
| Belongs to: |
|---|
| bZIP family |
Alternative Names
basic leucine zipper transcription factor MafG; hMAF; MafG; MGC13090; MGC20149; transcription factor MafG; v-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein G; v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian); V-maf musculoaponeurotic fibrosarcoma oncogene homolog G
Molecular Weight
Mass (kDA):
17.85 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17q25.3 |
| Sequence: | 17; NC_000017.11 (81918270..81927735, complement) |
Tissue Specificity
Highly expressed in skeletal muscle. Also expressed in heart and brain.
Subcellular Localizations
Nucleus.
Diseases
- Malignant Neoplasm Of Lung
- Malignant Neoplasms
- Neoplasms
- Lung Neoplasms
- Hypoxia
- Placental Choriocarcinoma
- Fibrosarcoma
- Injury To Liver
- Trophoblastic Neoplasms
- Nervousness
- Cell Transformation, Neoplastic
- Nerve Degeneration
- Nervous System Disorder
Interacting Proteins
- BACH1
- NFE2L1
- NFE2L2
- NFE2L3
Pathways
- Localization
- Platelet Formation
- Cell Differentiation
- Oncogenesis
- Transport
- Cellular Homeostasis
- Response To Hypoxia
- Regulation Of Gene Expression
- Liver Development
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MAFG
bosterbio.com/bosterbio-gene-info-cards/MAFG
References
PMID: 9195958 by Marini M.G., et al. hMAF, a small human transcription factor that heterodimerizes specifically with Nrf1 and Nrf2.
PMID: 9166829 by Blank V., et al. Human MafG is a functional partner for p45 NF-E2 in activating globin gene expression.