Alpha-mannosidase 2x Antibodies

AND MAN2A2 ELISA kits, Alpha-mannosidase 2x Proteins

Many biological assays use antibodies to detect Alpha-mannosidase 2x, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Alpha-mannosidase 2x in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Alpha-mannosidase 2x antibodies...

We validate the specificity of these antibodies to Alpha-mannosidase 2x by testing them on tissues known to express MAN2A2 positively and negatively. Browse below to find the MAN2A2 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MAN2A2 Infographic by Boster Bio

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MAN2A2 Overview

Facts about Alpha-mannosidase 2x.

MAN2A2 3D structure. Source: alphafold

Alpha-mannosidase 2x (MAN2A2)

Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway.

Gene Information

Human
Gene Name:	MAN2A2
Uniprot:	P49641
Entrez:	4122

Family

Belongs to:

glycosyl hydrolase 38 family

Alternative Names

alpha-mannosidase 2x; alpha-mannosidase IIx; MAN IIx; MANA2X; mannosidase, alpha type II-X; mannosidase, alpha, class 2A, member 2; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase; manosidase, alpha-, type II, isozyme X

Molecular Weight

Mass (kDA):
130.539 kDA

Genomic Context


Human

Location:	15q26.1
Sequence:	15; NC_000015.10 (90902377..90922585)

Subcellular Localizations

Golgi apparatus membrane; Single-pass type II membrane protein.

Diseases

Tissue Adhesions
Infertility
Male Infertility
Neoplasm Metastasis
Malignant Neoplasms
Neoplasms
Respiratory Failure
Glioma
Glioblastoma

Malignant Paraganglionic Neoplasm
Malignant Glioma
Brain Neoplasms

Pathways

Spermatogenesis
N-glycan Processing
Cell Adhesion
Secretory Pathway
Glycosylation
Cell-cell Adhesion

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MAN2A2

References

PMID: 8524845 by Misago M., et al. Molecular cloning and expression of cDNAs encoding human alpha- mannosidase II and a previously unrecognized alpha-mannosidase IIx isozyme.