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Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors. Regulates inflammation-induced expression of serum amyloid A proteins.
|Sequence:||16; NC_000016.10 (29806081..29811171)|
Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex and midfrontal cortex (at protein level).
Nucleus. In brains of Alzheimer disease patients, present in a plaque-like structures.