Mannose-binding protein A Antibodies

AND Mbl1 ELISA kits, Mannose-binding protein A Proteins

Many biological assays use antibodies to detect Mannose-binding protein A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Mannose-binding protein A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Mannose-binding protein A antibodies...

We validate the specificity of these antibodies to Mannose-binding protein A by testing them on tissues known to express Mbl1 positively and negatively. Browse below to find the Mbl1 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Mbl1 Infographic by Boster Bio

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Mbl1 Overview

Facts about Mannose-binding protein A.

Mbl1 3D structure. Source: alphafold

Mannose-binding protein A (Mbl1)

Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway.

Binds to late apoptotic cells, and to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages (By similarity). .

Gene Information

Mouse
Gene Name:	Mbl1
Uniprot:	P39039
Entrez:	17194

Family

Belongs to:

No superfamily

Alternative Names

MBL1; MBL-1; MBL-A; MBP-A; p28b; RaRF p28B; S-MBP

Molecular Weight

Mass (kDA):
25.396 kDA

Genomic Context


Mouse

Location:	14 B\|14 22.36 cM
Sequence:	14;

Diseases

Mastitis
Infective Disorder
Bacterial Infections
Mastitis, Bovine
Gestational Trophoblastic Neoplasms
Escherichia Coli Infections
Obesity
Hyperlipidemia

Swine Diseases
Staphylococcal Infections

Pathways

Complement Activation
Disease Resistance
Reverse Transcription
Translation
Lactation
Pathogenesis

PTMs

Disulfide bond

Glycoprotein

Hydroxylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Mbl1

References

PMID: 1712818 by Sastry K., et al. Molecular characterization of the mouse mannose-binding proteins. The mannose-binding protein A but not C is an acute phase reactant.

PMID: 1637828 by Kuge S., et al. cDNAs and deduced amino acid sequences of subunits in the binding component of mouse bactericidal factor, Ra-reactive factor: similarity to mannose-binding proteins.